Hematological investigations in a case of intravascular hemolysis due to infection

Anamarija Beljan, Viktorija Blagec, Ana Bronic, Marina Pavić

Preanalytical mysteries, Volume 34, Articles ahead of print

KEYWORDS: gas gangrene; ; hip prosthesis; hemolysis; case report

https://doi.org/10.11613/BM.2024.021001

A survey on the practice of phlebotomy in Lithuania and adherence to the EFLM-COLABIOCLI recommendations: continuous training and clear standard operating procedures as tools for better quality

Ricardas Stonys, Dalius Vitkus

Original articles, Volume 34, Articles ahead of print

KEYWORDS: preanalytical phase; phlebotomy; blood specimen collection; healthcare quality assurance

https://doi.org/10.11613/BM.2024.020702

Comparison of lipemia interference created with native lipemic material and intravenous lipid emulsion in emergency laboratory tests

Emel Çolak Samsum, Hatice Sürer, Serkan Bolat, Mehmet Şeneş, Doğan Yücel

Original articles, Volume 34, Articles ahead of print

KEYWORDS: lipemia; intravenous lipid emulsions; interference; clinical chemistry tests; preanalytical phase

https://doi.org/10.11613/BM.2024.020701

Prediction interval: A powerful statistical tool for monitoring patients and analytical systems

Abdurrahman Coskun

Lessons in biostatistics, Volume 34, Articles ahead of print

KEYWORDS: analytical performance; monitoring; personalized reference interval; prediction interval; reference change value

https://doi.org/10.11613/BM.2024.020101

Challenges of providing biochemistry results in a patient with Evans syndrome

Natividad Rico Ríos, Alison Bransfield, Caroline M Joyce, Mary R Cahill, Michelle O’Shaughnessy, Seán J. Costelloe

Preanalytical mysteries, Volume 34, February, Issue 1

KEYWORDS: Evans syndrome; hemolysis; hemolysis; case report

https://doi.org/10.11613/BM.2024.011001

Blood alcohol concentration in the clinical laboratory: a narrative review of the preanalytical phase in diagnostic and forensic testing

Cristiano Ialongo

Reviews, Volume 34, February, Issue 1

KEYWORDS: preanalytical phase; blood alcohol concentration; specimen handling; humans; substance abuse detection

https://doi.org/10.11613/BM.2024.010501

Changing the tide in vitamin D testing: An 8-year review of a demand management approach

Janne Cadamuro, Ursula Huber-Schönauer, Cornelia Mrazek, Lukas Hehenwarter, Ulrike Kipman, Thomas K. Felder, Christian Pirich

Letters to the editor, Volume 34, February, Issue 1

KEYWORDS: demand management; preanalytical phase; laboratory order; vitamin D

https://doi.org/10.11613/BM.2024.010401

Interference of anti-nuclear antibodies on determination of anti-neutrophil cytoplasmic antibodies in patients suspected of vasculitis: a case series

Mala Mahto, Neha Rai, Pulak Ranjan Das, Saurabh Karmakar, Divendu Bhushan

Preanalytical mysteries, Volume 33, October, Issue 3

KEYWORDS: anti-neutrophil cytoplasmic antibodies; anti-nuclear antibodies; interference; indirect immunofluorescence

https://doi.org/10.11613/BM.2023.031001

The LEAP checklist for laboratory evaluation and analytical performance characteristics reporting of clinical measurement procedures

Tze Ping Loh, Brian R Cooke, Thi Chi Mai Tran, Corey Markus, Rosita Zakaria, Chung Shun Ho, Elvar Theodorsson, Ronda F Greaves

Reviews, Volume 33, October, Issue 3

KEYWORDS: emerging technology(ies); method verification; method validation

https://doi.org/10.11613/BM.2023.030505

Coffee intake one hour prior to phlebotomy produces no clinically significant changes in routine biochemical test results

Silvia F Benozzi, Gisela Unger, Amparo Campion, Pablo G Milano, Graciela L Pennacchiotti

Original articles, Volume 33, June, Issue 2

KEYWORDS: fasting; coffee intake; blood sample collection; preanalytical variability; biochemical tests

https://doi.org/10.11613/BM.2023.020705

Analytical verification of the Dymind D7-CRP automated analyser

Merima Čolić, Bojana Magdić, Monika Kolundžić, Jasna Leniček Krleža

Original articles, Volume 33, June, Issue 2

KEYWORDS: blood cell count; C-reactive protein; haematology; verification

https://doi.org/10.11613/BM.2023.020703

Fibrin clot interference in a human chorionic gonadotrophin assay causing a false Down syndrome screening result

Arzu Etem Akagac, Hatice Bozkurt Yavuz

Preanalytical mysteries, Volume 33, February, Issue 1

KEYWORDS: hCG; prenatal screening; fibrin; preanalytical phase; case report

https://doi.org/10.11613/BM.2023.011001

Underfilled blood tube containing EDTA: Is it an inappropriate sample for HbA1c assay?

Berrak Guven, Ismail Benice, Murat Can

Short communications, Volume 33, February, Issue 1

KEYWORDS: HbA1c; blood sample collection; preanalytical error; diabetes mellitus

https://doi.org/10.11613/BM.2023.010901

A case of discrepant laboratory results in samples obtained from a central venous catheter and peripheral veins: when solving a pre-analytical mystery could improve patient care

Mattia Carini, Moira Micheletti, Giovanni Martellosio, Elisa Caravaggi, Nicola Portesi, Giorgio Biasiotto, Monica Marini, Duilio Brugnoni, Federico Serana

Preanalytical mysteries, Volume 32, October, Issue 3

KEYWORDS: blood specimen collection; pre-analytical phase; medical error; central venous catheters; haematology

https://doi.org/10.11613/BM.2022.031001

Inter-rater reliability assessment for the new-born screening quality assurance

Leonor Guiñón, Anna Soler, Rosa María López, Sonia Pajares, José Manuel González de Aledo, Ana Argudo-Ramírez, José Luis Marín, Judit García-Villoria, Ángeles Sahuquillo, Luisa Alvarez

Short communication, Volume 32, October, Issue 3

KEYWORDS: accreditation; extra-analytical phase; new-born screening; quality control

https://doi.org/10.11613/BM.2022.030901

Evaluation of preanalytical and postanalytical phases in clinical biochemistry laboratory according to IFCC laboratory errors and patient safety specifications

Nergiz Zorbozan, Orçun Zorbozan

Original articles, Volume 32, October, Issue 3

KEYWORDS: total quality management; preanalytical phase; quality indicators; six sigma

https://doi.org/10.11613/BM.2022.030701

Performance evaluation of the high sensitive troponin I assay on the Atellica IM analyser

Antonio Buño Soto, Katell Peoc’h, Tommaso Fasano, Jorge Diaz-Garzon, Bernardino González de la Presa, Valerie Chicha-Cattoir, Simone Canovi, Maria Sanz de Pedro, Nayra Rico, Tiphaine Robert, Efrem Bonelli, Pilar Fernández Calle, Aurea Mira, Guillaume Lefevre, Luigi Vecchia, Jose Luis Bedini

Original articles, Volume 32, June, Issue 2

KEYWORDS: analytical techniques and equipment; high-sensitive troponin I; immunoassay; performance evaluation

https://doi.org/10.11613/BM.2022.020709

Detection of preanalytical errors in arterial blood gas analysis

Serap Çuhadar, Hayat Özkanay-Yörük, Mehmet Köseoğlu, Kaan Katırcıoğlu

Original articles, Volume 32, June, Issue 2

KEYWORDS: blood-gas analysis; plastic syringe; pO; pCO; preanalytical variables

https://doi.org/10.11613/BM.2022.020708

Post-collection acidification of spot urine sample is not needed before measurement of electrolytes

Tomáš Šálek, Pavel Musil, Marek Pšenčík, Vladimír Palička

Original articles, Volume 32, June, Issue 2

KEYWORDS: urolithiasis; calcium; magnesium; phosphorus; preanalytical phase

https://doi.org/10.11613/BM.2022.020702

A sudden creatinine increase: A case report

Bernhard Strasser, Sebastian Strasser, Josef Tomasits

Preanalytical mysteries, Volume 32, February, Issue 1

KEYWORDS: cystatin C; creatinine; estimated glomerular filtration rate; case report

https://doi.org/10.11613/BM.2022.011002

Deviating glucose results in an international dual-center study. A root cause investigation

Janne Cadamuro, Peter Bergsten, Katharina Mörwald, Anders Forslund, Marie Dahlbom, Jonas Bergquist, Iris Ciba, Susanne M. Brunner, Jeanne Jabbour, Daniel Weghuber

Preanalytical mysteries, Volume 32, February, Issue 1

KEYWORDS: preanalytical phase; tube additive; PREDICT; blood collection tubes; preanalytical error

https://doi.org/10.11613/BM.2022.011001

Interpretative comments - need for harmonization? Results of the Croatian survey by the Working Group for Post-analytics

Vladimira Rimac, Sonja Podolar, Anja Jokic, Jelena Vlasic Tanaskovic, Lorena Honovic, Jasna Lenicek Krleza

Short communications, Volume 32, February, Issue 1

KEYWORDS: post-analytical phase; clinical laboratory; interpretative comments; questionnaire

https://doi.org/10.11613/BM.2022.010901

Moving average procedures as an additional tool for real-time analytical quality control: challenges and opportunities of implementation in small-volume medical laboratories

Vera Lukić, Svetlana Ignjatović

Original articles, Volume 32, February, Issue 1

KEYWORDS: quality control; moving average; patient-based real-time quality control; laboratory information system

https://doi.org/10.11613/BM.2022.010705

Evaluation of the clinical chemistry tests analytical performance with Sigma Metric by using different quality specifications - Comparison of analyser actual performance with manufacturer data

Murat Keleş

Original articles, Volume 32, February, Issue 1

KEYWORDS: Six Sigma; total allowable error; quality control; biological variation

https://doi.org/10.11613/BM.2022.010703

Review of current incidents and risk calculations used in the Royal College of Australasian Pathologists Key Incident Management and Monitoring Systems - a system that could be used by all Australasian medical laboratories, and easily adapted to worldwide use

Stephanie Gay, Belinda Pope, Tony Badrick, Michael Whiley

Original articles, Volume 32, February, Issue 1

KEYWORDS: extra-analytical phase; laboratory organisation and management; pre- and post-analytical incidents; risk matrix; quality assurance

https://doi.org/10.11613/BM.2022.010702

The concurrence of the current postanalytical phase management with the national recommendations: a survey of the Working Group for Postanalytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Anja Jokic, Vladimira Rimac, Jelena Vlasic Tanaskovic, Sonja Podolar, Lorena Honovic, Jasna Lenicek Krleza

Original articles, Volume 31, October, Issue 3

KEYWORDS: postanalytical phase; survey; clinical laboratory; critical results; quality indicators

https://doi.org/10.11613/BM.2021.030704

Comparison of Freelite and N-Latex serum free light chain assays: a critical review

Massimo Daves, Andrea Piccin, Vincenzo Roccaforte, Giuseppe Lippi

Original Articles, Volume 31, October, Issue 3

KEYWORDS: free light chain; monoclonal gammopathies; analytical techniques and equipment; comparison; immunoassays

https://doi.org/10.11613/BM.2021.030701

The missing slope: paradoxical shortening of activated partial thromboplastin time in a patient on unfractionated heparin therapy

Ivana Lapić, Ana Lončar Vrančić, Désirée Coen Herak, Dunja Rogić

Preanalytical Mysteries, Volume 31, June, Issue 2

KEYWORDS: pre-analytical phase; hemostasis; activated partial thromboplastin time; unfractionated heparin

https://doi.org/10.11613/BM.2021.021003

Delayed diagnosis and treatment of extreme hypertriglyceridemia due to rejection of a lipemic sample

Jan Van Elslande, Samira Hijjit, Katrien De Vusser, Michel Langlois, Björn Meijers, Ann Mertens, Bart Van der Schueren, Glynis Frans, Pieter Vermeersch

Preanalytical Mysteries, Volume 31, June, Issue 2

KEYWORDS: extra-analytical phase; hypertriglyceridemia; interferences; lipemia; lipoprotein metabolism

https://doi.org/10.11613/BM.2021.021002

Detection of monoclonal protein by capillary zone electrophoresis can be challenged by iodinated contrast agent interference: a case report

Clément Capaldo, Mourad Cheddad El Aouni, Damien Laurelli, Cyril Leven, Jean-Luc Carré

Preanalytical Mysteries, Volume 31, June, Issue 2

KEYWORDS: capillary electrophoresis; interference; iodinated contrast; gammopathy; case report

https://doi.org/10.11613/BM.2021.021001

The rise in preanalytical errors during COVID-19 pandemic

Tapasyapreeti Mukhopadhyay, Arulselvi Subramanian, Shivam Pandey, Nirupam Madaan, Anjan Trikha, Rajesh Malhotra

Original Articles, Volume 31, June, Issue 2

KEYWORDS: laboratory biosafety; preanalytical phase; quality indicators; SARS-CoV-2; total testing process

https://doi.org/10.11613/BM.2021.020710

Order of draw of blood samples affect potassium results without K-EDTA contamination during routine workflow

Şerif Ercan, Bahri Ramadan, Ozan Gerenli

Original Articles, Volume 31, June, Issue 2

KEYWORDS: EDTA contamination; order of draw; patient safety; phlebotomy; preanalytical phase; pseudohyperkalaemia

https://doi.org/10.11613/BM.2021.020704

Utility of icteric index in clinical laboratories: more than a preanalytical indicator

Rufino Mondejar, María Mayor Reyes, Enrique Melguizo Madrid, Consuelo Cañavate Solano, Santiago Pérez Ramos

Original Articles, Volume 31, June, Issue 2

KEYWORDS: jaundice; bilirubin; hyperbilirubinemia; haemolysis; receiver operating characteristic curve

https://doi.org/10.11613/BM.2021.020703

Pre-analytical mysteries: A case of severe hypervitaminosis D and mild hypercalcaemia

Emma Whittle, Elzahn de Waal, Tony Huynh, Oliver Treacy, Adam Morton

Preanalytical mysteries, Volume 31, February, Issue 1

KEYWORDS: endocrinology; hypercalcaemia; hypervitaminosis D; interferences; paraprotein

https://doi.org/10.11613/BM.2021.011001

Effect of haemolysis on an enzymatic measurement of ethanol

Abdulkadir Çat, Kamil Taha Uçar, Alper Gümüş

Original Articles, Volume 31, February, Issue 1

KEYWORDS: ethanol; haemolysis; interference; preanalytical error

https://doi.org/10.11613/BM.2021.010704

Verification of automated latex-enhanced particle immunoturbidimetric D-Dimer assays on different analytical platforms and comparability of test results

Ivana Lapić, Désirée Coen Herak, Snježana Prpić, Andrea Prce, Vanja Raščanec, Renata Zadro, Dunja Rogić

Original Articles, Volume 30, October, Issue 3

KEYWORDS: haemostasis; blood coagulation tests; D-Dimer; immunoturbidimetry; validation study

https://doi.org/10.11613/BM.2020.030705

Analytical bias of automated immunoassays for six serum steroid hormones assessed by LC-MS/MS

Željko Debeljak, Ivana Marković, Jasna Pavela, Iva Lukić, Dario Mandić, Sanja Mandić, Vesna Horvat, Vatroslav Šerić

Original Articles, Volume 30, October, Issue 3

KEYWORDS: steroid hormone; immunoassay; bias; LC-MS/MS; method comparison

https://doi.org/10.11613/BM.2020.030701

Experience on how to implement a preanalytical and POCT unit in Madrid’s IFEMA field hospital during this unprecedented COVID-19 emergency

Jorge Díaz–Garzón, Paloma Oliver, Gema Crespo, Marta Duque, Pilar Fernandez-Calle, Marta Gómez, Roberto Mora, Isabel Moreno, Lydia Pascual, Ana-Laila Qasem, Olaia Rodriguez-Fraga, Manuela Simón, Antonio Buño

Letter to the editor, Volume 30, October, Issue 3

KEYWORDS: COVID-19; field hospital; laboratory organization and management; preanalytics; POCT

https://doi.org/10.11613/BM.2020.030403

Corrigendum to: Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain

Isabel García-del-Pino, Josep M. Bauça, Carolina Gómez, Andrea Caballero, María Antonia Llopis, Mercedes Ibarz, Débora Martínez, Montserrat Ventura, Itziar Marzana, Juan J. Puente, Marta Segovia, Paloma Salas, Rubén Gómez-Rioja

Corrigendum, Volume 30, June, Issue 2

https://doi.org/10.11613/BM.2020.021201

A case of severe pseudohyperkalaemia due to muscle contraction

Jan Van Elslande, Toon Dominicus, Jaan Toelen, Glynis Frans, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, June, Issue 2

KEYWORDS: hyperkalaemia; pseudohyperkalaemia; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.021004

Case report of a phantom pheochromocytoma

Caroline M Joyce, Audrey Melvin, Paula M O’Shea, Seán J Costelloe, Domhnall J O’Halloran

Preanalytical Mysteries, Volume 30, June, Issue 2

KEYWORDS: case report; pheochromocytoma; metanephrines; false positive; sulfasalazine

https://doi.org/10.11613/BM.2020.021003

Dark brown serum and plasma samples: a case report

Lora Dukic, Nikolina Maric, Ana-Maria Simundic

Preanalytical mysteries, Volume 30, June, Issue 2

KEYWORDS: case report; critical care; extra-analytical phase; sample coloration

https://doi.org/10.11613/BM.2020.021002

Case report of spuriously low sodium and calcium in a 36-year-old male in primary care

Seán J. Costelloe, Kelly McCarthy, Marguerite O’Connell, Mark Butler

Preanalytical mysteries, Volume 30, June, Issue 2

KEYWORDS: delayed separation; spurious hyponatraemia; spurious hypocalcaemia; haemolysis; case report

https://doi.org/10.11613/BM.2020.021001

Quality improvement project: Reducing non-conformities of the samples for haemostasis testing in a secondary healthcare centre through the nurses’ education in phlebotomy

Patricija Banković Radovanović

Original Articles, Volume 30, June, Issue 2

KEYWORDS: quality improvement; phlebotomy; education; pre-analytical phase

https://doi.org/10.11613/BM.2020.020708

Survey on request form content and result reporting in therapeutic drug monitoring service among laboratories in Czechia and Slovakia

Tomáš Šálek, Petr Schneiderka, Barbora Studená, Michaela Votroubková

Original Articles, Volume 30, June, Issue 2

KEYWORDS: drug monitoring; pharmacokinetics; preanalytical phase; clinical laboratory services; kidney function tests

https://doi.org/10.11613/BM.2020.020706

Changes in error rates in the Australian key incident monitoring and management system program

Stephanie Gay, Tony Badrick

Original papers, Volume 30, June, Issue 2

KEYWORDS: preanalytical errors; postanalytical errors; preanalytical risk; postanalytical risk

https://doi.org/10.11613/BM.2020.020704

Analytical performance assessment and improvement by means of the Failure mode and effect analysis (FMEA)

Leonor Guiñón, Anna Soler, Mónica Gisell Díaz, Rosa María Fernández, Nayra Rico, Josep Lluís Bedini, Aurea Mira, Luisa Alvarez

Original papers, Volume 30, June, Issue 2

KEYWORDS: risk management; FMEA; sigma metric; analytical performance; quality control

https://doi.org/10.11613/BM.2020.020703

General position of Croatian medical biochemistry laboratories on autovalidation: survey of the Working Group for Post-analytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Vladimira Rimac, Anja Jokic, Sonja Podolar, Jelena Vlasic Tanaskovic, Lorena Honovic, Jasna Lenicek Krleza

Original papers, Volume 30, June, Issue 2

KEYWORDS: postanalytical phase; autovalidation; clinical laboratory; questionnaire

https://doi.org/10.11613/BM.2020.020702

Long-term stability of clinically relevant chemistry analytes in pleural and peritoneal fluid

Lara Milevoj Kopcinovic, Marija Brcic, Alen Vrtaric, Adriana Unic, Marija Bozovic, Nora Nikolac Gabaj, Marijana Miler, Jelena Culej

Original papers, Volume 30, June, Issue 2

KEYWORDS: stability; pleural effusion; peritoneal effusion; preanalytical phase

https://doi.org/10.11613/BM.2020.020701

Errors within the total laboratory testing process, from test selection to medical decision-making – A review of causes, consequences, surveillance and solutions

Cornelia Mrazek, Giuseppe Lippi, Martin H Keppel, Thomas K Felder, Hannes Oberkofler, Elisabeth Haschke-Becher, Janne Cadamuro

Review, Volume 30, June, Issue 2

KEYWORDS: total testing process; extra-analytical phase; quality indicators; laboratory medicine; patient safety

https://doi.org/10.11613/BM.2020.020502

In sickness and in health: pivotal role of vitamin D

Nora Nikolac Gabaj, Adriana Unic, Marijana Miler, Tomislav Pavicic, Jelena Culej, Ivan Bolanca, Davorka Herman Mahecic, Lara Milevoj Kopcinovic, Alen Vrtaric

Review, Volume 30, June, Issue 2

KEYWORDS: vitamin D; preanalytical variability; diabetes mellitus; polymorphism; fertility; extravascular body fluids

https://doi.org/10.11613/BM.2020.020501

The effect of jet-lag on serum concentrations of thyroid stimulating hormone and prolactin: A case report

Merve Sibel Gungoren, Deniz Ilhan Topcu, Cevdet Zungun

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: preanalytical phase; case report; jet-lag; thyroid stimulating hormone; prolactin

https://doi.org/10.11613/BM.2020.011003

Unexpected abnormal coagulation test results in a 2-year-old child: A case report

Patricija Banković Radovanović, Tanja Živković Mikulčić, Jasmina Simović Medica

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: case report; preanalytical phase; sample collection; coagulation

https://doi.org/10.11613/BM.2020.011002

High anion gap metabolic acidosis caused by D-lactate: mind the time of blood collection

Matthias Weemaes, Martin Hiele, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: D-lactate; D-lactic acidosis; high anion gap acidosis; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.011001

Six Sigma revisited: We need evidence to include a 1.5 SD shift in the extraanalytical phase of the total testing process

Abdurrahman Coskun, Cristiano Ialongo

Short Communication, Volume 30, February, Issue 1

KEYWORDS: extraanalytical phase; shift; Sigma metric; Six Sigma; total testing process

https://doi.org/10.11613/BM.2020.010901

Analytical verification and comparison of chromogenic assays for dabigatran, rivaroxaban and apixaban determination on BCSXP and STA Compact Max analysers

Ivana Ćelap, Sandra Margetić, Marija Brčić, Roman Mihić

Original Articles, Volume 30, February, Issue 1

KEYWORDS: chromogenic assay; dabigatran; rivaroxaban; apixaban; method comparison

https://doi.org/10.11613/BM.2020.010706

Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain

Isabel García-del-Pino, Josep M. Bauça, Carolina Gómez, Andrea Caballero, María Antonia Llopis, Mercedes Ibarz, Débora Martínez, Montserrat Ventura, Itziar Marzana, Juan J. Puente, Marta Segovia, Paloma Salas, Rubén Gómez-Rioja

Original Articles, Volume 30, February, Issue 1

KEYWORDS: glucose; preanalytical phase; glycolysis; diabetes mellitus; survey

https://doi.org/10.11613/BM.2020.010704

Study of the preanalytical variables affecting the measurement of clinically relevant free-circulating microRNAs: focus on sample matrix, platelet depletion, and storage conditions

Martina Faraldi, Veronica Sansoni, Silvia Perego, Marta Gomarasca, Jakub Kortas, Ewa Ziemann, Giuseppe Banfi, Giovanni Lombardi

Original Articles, Volume 30, February, Issue 1

KEYWORDS: circulating microRNA; biomarkers; plasma; preanalytical phase

https://doi.org/10.11613/BM.2020.010703

Corrigendum to: Analytical evaluation of the new Seal Autoanalyzer 3 High Resolution for urinary iodine determination

Valentina Vidranski, Maja Franceschi, Dražena Krilić, Tomislav Jukić, Ivan Mihaljević, Zvonko Kusić

Corrigendum, Volume 29, October, Issue 3

https://doi.org/10.11613/BM.2019.031201

Flushing of an intravenous catheter: a cause for unreliable laboratory results

Rutger C.C. Hengeveld, Maaike C. Gerards, Bianca E. Olofsen, Milan L. Ridderikhof, Victor F.H.A. Hakkenberg van Gaasbeek, Peter A. Leenhouts, Edmée C. van Dongen-Lases

Preanalytical Mysteries, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; phlebotomy; intravenous catheter

https://doi.org/10.11613/BM.2019.031001

Clinician’s opinion about critical risk results proposed by the Croatian Chamber of Medical Biochemists: a survey in one Croatian tertiary hospital

Pavica Šonjić, Ana Nikler, Dora Vuljanić, Lora Dukić, Ana-Maria Šimundić

Original Articles, Volume 29, October, Issue 3

KEYWORDS: critical results; survey; post-analytical phase; laboratory management

https://doi.org/10.11613/BM.2019.030711

Time-dependent variation of ionized calcium in serum samples

Antonija Perović, Marina Njire Bratičević

Original Articles, Volume 29, October, Issue 3

KEYWORDS: ionized calcium; serum; heparin; specimen handling; pre-analytical phase

https://doi.org/10.11613/BM.2019.030708

Effectiveness of minimum retesting intervals in managing repetitive laboratory testing: experience from a Croatian university hospital

Ivana Lapić, Dunja Rogić, Mirjana Fuček, Ružica Galović

Original Articles, Volume 29, October, Issue 3

KEYWORDS: evidence-based practice; clinical laboratory services; pre-analytical phase; cost analysis

https://doi.org/10.11613/BM.2019.030705

Assessment of the degree of adherence of medical laboratories to KDIGO 2012 guideline for evaluation and management of CKD in Czechia and Slovakia

Šálek Tomáš, Friedecký Bedřich, Kratochvíla Josef, Pelinková Květa, Budina Marek

Original Articles, Volume 29, October, Issue 3

KEYWORDS: creatinine; cystatin C; glomerular filtration; estimated glomerular filtration rate; post-analytical phase

https://doi.org/10.11613/BM.2019.030704

Preanalytical classical and alternative complement pathway activity loss

Koen O.A. Vercauteren, Stijn Lambrecht, Joris Delanghe

Original Articles, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; alternative and classical complement pathway; complement haemolytic activity assay; complement C3; complement C3d

https://doi.org/10.11613/BM.2019.030701

An abrupt rise of coagulation error messages on ACL TOP automated analysers

Bas Calcoen, Koen Desmet, Pieter Vermeersch

Preanalytical Mysteries, Volume 29, June, Issue 2

KEYWORDS: preanalytical phase; blood coagulation test; diagnostic error; blood specimen collection

https://doi.org/10.11613/BM.2019.021002

Description of interference in the measurement of troponin T by a high-sensitivity method

Miguel Aliste-Fernández, Gemma Sole-Enrech, Ruth Cano-Corres, Silvia Teodoro-Marin, Eugenio Berlanga-Escalera

Preanalytical Mysteries, Volume 29, June, Issue 2

KEYWORDS: high-sensitivity troponin T; interference; case report

https://doi.org/10.11613/BM.2019.021001

Analytical evaluation of the new Seal Autoanalyzer 3 High Resolution for urinary iodine determination

Valentina Vidranski, Maja Franceschi, Dražena Krilić, Tomislav Jukić, Ivan Mihaljević, Zvonko Kusić

Original Articles, Volume 29, June, Issue 2

KEYWORDS: colorimetry; iodine; method evaluation; urine

https://doi.org/10.11613/BM.2019.020711

Effect of temperature and time delay in centrifugation on stability of select biomarkers of nutrition and non-communicable diseases in blood samples

Ransi Ann Abraham, Praween K. Agrawal, Rajib Acharya, Avina Sarna, Sowmya Ramesh, Robert Johnston, Arjan de Wagt, Nizamuddin Khan, Akash Porwal, Sucheta Banerjee Kurundkar, Arvind Pandey, Raghu Pullakhandam, Krishnapillai Madhavan Nair, Geeta Trilok Kumar

Original Articles, Volume 29, June, Issue 2

KEYWORDS: survey; preanalytical conditions; temperature; time delay; centrifugation

https://doi.org/10.11613/BM.2019.020708

European survey on preanalytical sample handling – Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020705

European survey on preanalytical sample handling – Part 1: How do European laboratories monitor the preanalytical phase? On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Janne Cadamuro, Giuseppe Lippi, Alexander von Meyer, Mercedes Ibarz, Edmee van Dongen, Michael Cornes, Mads Nybo, Pieter Vermeersch, Kjell Grankvist, Joao Tiago Guimaraes, Gunn B.B. Kristensen, Barbara de la Salle, Ana-Maria Simundic

Original Articles, Volume 29, June, Issue 2

KEYWORDS: preanalytics; standardization; survey

https://doi.org/10.11613/BM.2019.020704

Evaluation of a commercial liquid-chromatography high-resolution mass-spectrometry method for the determination of hepcidin-25

Dietmar Enko, Sieglinde Zelzer, Günter Fauler, Markus Herrmann

Original articles, Volume 29, June, Issue 2

KEYWORDS: hepcidin-25; preanalytical phase; protein biomarker; liquid-chromatography high-resolution mass-spectrometry

https://doi.org/10.11613/BM.2019.020701

Post-analytical laboratory work: national recommendations from the Working Group for Post-analytics on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Jasna Lenicek Krleza, Lorena Honovic, Jelena Vlasic Tanaskovic, Sonja Podolar, Vladimira Rimac, Anja Jokic

Review, Volume 29, June, Issue 2

KEYWORDS: recommendations; post-analytical phase; clinical laboratory; harmonization; test report

https://doi.org/10.11613/BM.2019.020502

A paradigmatic case of haemolysis and pseudohyperkalemia in blood gas analysis

Gian Luca Salvagno, Davide Demonte, Giuseppe Lippi

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: potassium; hyperkalemia; preanalytical variability; diagnostic errors

https://doi.org/10.11613/BM.2019.011003

Case report: An index of suspicion in hyponatraemia

Marizna Barkhuizen, Mariza Hoffmann, Ekkehard WA Zöllner, Rajiv T. Erasmus, Annalise E. Zemlin

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: pseudohyponatraemia; electrolyte exclusion effect; case report; serum indices; endogenous interference

https://doi.org/10.11613/BM.2019.011002

Falsely prolonged activated partial thromboplastin time – a pre- and post-analytical issue

Charlotte Gils, Pernille Just Vinholt, Mads Nybo

Preanalytical Mysteries, Volume 29, February, Issue 1

KEYWORDS: activated partial thromboplastin time; haemolysis; lipemia; post-analytical errors; pre-analytical errors

https://doi.org/10.11613/BM.2019.011001

Plasma free DNA: Evaluation of temperature-associated storage effects observed for Roche Cell-Free DNA collection tubes

Dietmar Enko, Gabriele Halwachs-Baumann, Gernot Kriegshäuser

Short Communications, Volume 29, February, Issue 1

KEYWORDS: cell-free nucleic acids; pre-analytical phase; quality improvement

https://doi.org/10.11613/BM.2019.010904

Effects of different anticoagulants on glycated albumin quantification

Graziella Bonetti, Nicola Di Gaetano, Renata Paleari, Ferruccio Ceriotti

Short Communications, Volume 29, February, Issue 1

KEYWORDS: preanalytical phase; serum albumin; diabetes mellitus; anticoagulants

https://doi.org/10.11613/BM.2019.010901

Analytical verification of 12 most commonly used urine dipsticks in Croatia: comparability, repeatability and accuracy

Dora Vuljanić, Ana Dojder, Valentina Špoljarić, Andrea Saračević, Lora Dukić, Jasna Leniček-Krleža, Jelena Vlašić-Tanasković, Ivana Maradin, Ana Grzunov, Željka Vogrinc, Ana-Maria Šimundić

Original Articles, Volume 29, February, Issue 1

KEYWORDS: verification; urine dipsticks; comparability; accuracy; repeatability

https://doi.org/10.11613/BM.2019.010708

Faecal calprotectin determination: impact of preanalytical sample treatment and stool consistency on within- and between-method variability

Gordana Juricic, Tina Brencic, Andrea Tesija-Kuna, Milena Njegovan, Lorena Honovic

Original Articles, Volume 29, February, Issue 1

KEYWORDS: calprotectin; preanalytical phase; inflammatory bowel disease; immunoassay

https://doi.org/10.11613/BM.2019.010707

Confidence interval for quantiles and percentiles

Cristiano Ialongo

Lessons in Biostatistics, Volume 29, February, Issue 1

KEYWORDS: biostatistics; statistical methods; confidence intervals; extra-analytical phase

https://doi.org/10.11613/BM.2019.010101

Effect of cold agglutinins on red blood cell parameters in a trauma patient: a case report

Anita Topic, Lara Milevoj Kopcinovic, Ana Bronic, Marina Pavic

Preanalytical mysteries, Volume 28, October, Issue 3

KEYWORDS: cold agglutinins; preanalytical errors; red blood cell count; spurious complete blood count results

https://doi.org/10.11613/BM.2018.031001

Biotin and high-sensitivity cardiac troponin T assay

Aurélien Schrapp, François Fraissinet, Charles Hervouet, Hélène Girot, Valéry Brunel

Short Communication, Volume 28, October, Issue 3

KEYWORDS: troponin T; biotin; multiple sclerosis; preanalytical phase

https://doi.org/10.11613/BM.2018.030901

A collaborative study by the Working Group on Hemostasis and Thrombosis of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) on the interference of haemolysis on five routine blood coagulation tests by evaluation of 269

Chiara Novelli, Matteo Vidali, Bruno Brando, Benedetto Morelli, Giovanna Andreani, Marina Arini, Paola Calzoni, Roberta Giacomello, Barbara Montaruli, Emanuela Muccini, Angela Papa, Paola Pradella, Lucia Ruocco, Fosca Siviero, Filomena Gemma Viola, Mario

Original Papers, Volume 28, October, Issue 3

KEYWORDS: blood coagulation tests; haemolysis; preanalytical phase

https://doi.org/10.11613/BM.2018.030711

Evaluation of the analytical performances of the Cobas c513 analyser for HbA1c assay

Stéphane Jaisson, Nathalie Leroy, Michel Soulard, Aurore Desmons, Emmanuelle Guillard, Philippe Gillery

Original Papers, Volume 28, October, Issue 3

KEYWORDS: diabetes; evaluation; HbA; immunoassay

https://doi.org/10.11613/BM.2018.030708

Haematology specimen acceptability: a national survey in Chinese laboratories

Yuanyuan Ye, Wei Wang, Haijian Zhao, Falin He, Kun Zhong, Shuai Yuan, Yuxuan Du, Bingquan Chen, Zhiguo Wang

Original Papers, Volume 28, October, Issue 3

KEYWORDS: quality indicator; preanalytical phase; quality control; haematology; survey

https://doi.org/10.11613/BM.2018.030704

Evaluating analytical quality in clinical biochemistry laboratory using Six Sigma

Xuehui Mao, Jing Shao, Bingchang Zhang, Yong Wang

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Sigma metrics; total allowable error; quality control; bias

https://doi.org/10.11613/BM.2018.020904

Using Sigma metrics to establish analytical product performance requirements and optimize analytical performance of an diagnostic assay using a theoretical total PSA assay as an example

Victoria Petrides, Sharon Schneider

Short Communications: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; decision making; goals

https://doi.org/10.11613/BM.2018.020903

Storage stability of commonly used haematological parameters at 33 °C

Ashish Jain, Sanchit Jain, Neha Singh, Priyanka Aswal, Shweta Pal, Sushant Kumar Meinia, Nilotpal Chowdhury

Short Communications, Volume 28, June, Issue 2

KEYWORDS: pre-analytical error; erythrocyte indices; laboratory errors; platelet count; sample stability

https://doi.org/10.11613/BM.2018.020901

Utilization of a healthcare failure mode and effects analysis to identify error sources in the preanalytical phase in two tertiary hospital laboratories

Adolfo Romero, Juan Gómez-Salgado, Adolfo Romero-Arana, Carlos Ruiz-Frutos

Original Papers, Volume 28, June, Issue 2

KEYWORDS: preanalytical phase; Healthcare Failure Mode and Effects Analysis; quality assessment; errors

https://doi.org/10.11613/BM.2018.020713

Evaluation of the analytical performances of Cobas 6500 and Sysmex UN series automated urinalysis systems with manual microscopic particle counting

Ebubekir Bakan, Zafer Bayraktutan, Nurcan Kilic Baygutalp, Mehmet Ali Gul, Fatma Zuhal Umudum, Nuri Bakan

Original Papers, Volume 28, June, Issue 2

KEYWORDS: urinalysis; automated urinalysis; manual microscopy

https://doi.org/10.11613/BM.2018.020712

Comprehensive evaluation of the internal and external quality control to redefine analytical quality goals

Beatriz Varela, Gonzalo Pacheco

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: total quality management; quality control; bias; laboratory proficiency testing/methods; clinical chemistry test

https://doi.org/10.11613/BM.2018.020710

Sigma metrics for assessing the analytical quality of clinical chemistry assays: a comparison of two approaches

Xiuzhi Guo, Tianjiao Zhang, Xuehui Gao, Pengchang Li, Tingting You, Qiong Wu, Jie Wu, Fang Zhao, Liangyu Xia, Ermu Xu, Ling Qiu, Xinqi Cheng

Original Papers: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma; proficiency testing; internal quality control; allowable total error

https://doi.org/10.11613/BM.2018.020708

The impact of delayed sample handling and type of anticoagulant on the interpretation of dysplastic signs detected by flow cytometry

Bettina Kárai, Zsófia Miltényi, Lajos Gergely, Marianna Száraz-Széles, János Kappelmayer, Zsuzsanna Hevessy

Original Papers, Volume 28, June, Issue 2

KEYWORDS: myelodysplastic syndromes; flow cytometry; pre-analytical error

https://doi.org/10.11613/BM.2018.020704

Effect of different pre-analytical conditions on plasma lactate concentration

Ivana Rako, Ana Mlinaric, Monika Dozelencic, Gordana Fressl Juros, Dunja Rogic

Original Papers, Volume 28, June, Issue 2

KEYWORDS: plasma lactate; blood analysis; blood specimen collection; haemolysis; pre-analytical phase

https://doi.org/10.11613/BM.2018.020701

Analytical Sigma metrics: A review of Six Sigma implementation tools for medical laboratories

Sten Westgard, Hassan Bayat, James O Westgard

Review: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: Six Sigma metrics; quality control frequency; OPSpecs chart; method decision chart; Westgard rules

https://doi.org/10.11613/BM.2018.020502

Expected long-term defect rate of analytical performance in the medical laboratory: Assured Sigma versus observed Sigma

Hassan Bayat

Lessons in Biostatistics: Special issue on Six Sigma metrics, Volume 28, June, Issue 2

KEYWORDS: medical laboratory; Sigma metrics; Six Sigma; allowable total error

https://doi.org/10.11613/BM.2018.020101

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Tomáš Šálek

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: hyperkalemia; case report; electrolytes; pseudohyperkalemia

https://doi.org/10.11613/BM.2018.011002

Elevated zinc concentrations in a 5 months old infant: A case report

Eva Rabing Brix Petersen, Sven Mortensen, Mads Nybo

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: capillary blood sample; case report; pre-analytical phase; zinc

https://doi.org/10.11613/BM.2018.011001

Preanalytics of urine sediment examination: effect of relative centrifugal force, tube type, volume of sample and supernatant removal

Amalija Bunjevac, Nora Nikolac Gabaj, Marijana Miler, Anita Horvat

Original Papers, Volume 28, February, Issue 1

KEYWORDS: preanalytical phase; laboratory error; urinalysis; urine sediment

https://doi.org/10.11613/BM.2018.010707

Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dangan Yang

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytical phase; venous blood sampling; knowledge; nurses; phlebotomy

https://doi.org/10.11613/BM.2018.010703

Fasting conditions: Influence of water intake on clinical chemistry analytes

Silvia F. Benozzi, Gisela Unger, Amparo Campion, Graciela L. Pennacchiotti

Original Papers, Volume 28, February, Issue 1

KEYWORDS: fasting; water intake; blood sample collection; preanalytical variability; clinical chemistry tests

https://doi.org/10.11613/BM.2018.010702

External Quality Assessment beyond the analytical phase: an Australian perspective

Tony Badrick, Stephanie Gay, Euan J. McCaughey, Andrew Georgiou

Special Issue: External Quality Assessment in Laboratory Medicine - Review, Volume 27, February, Issue 1

KEYWORDS: health care quality assurance; laboratory; pathology; quality

https://doi.org/10.11613/BM.2017.009

What´s floating on my plasma?

Janne Cadamuro, Helmut Wiedemann, Thomas K. Felder, Cornelia Mrazek, Ulrike Kipman, Oberkofler Hannes, Elisabeth Haschke-Becher

Pre-analytical mysteries, Volume 27, June, Issue 2

KEYWORDS: case report; white particulate matter; lithium-heparin tubes; separator gel

https://doi.org/10.11613/BM.2017.047

Case report of unexplained hypocalcaemia in a slightly haemolysed sample

Michael Cornes

Pre-analytical mysteries, Volume 27, June, Issue 2

KEYWORDS: case report; pre-analytical; contamination; K-EDTA

https://doi.org/10.11613/BM.2017.046

Acutely developing, spurious anaemia without actual blood loss. A paradigmatic case report

Giuseppe Lippi, Gianfranco Cervellin

Pre-analytical mysteries, Volume 27, June, Issue 2

KEYWORDS: anaemia; errors; posture; preanalytical variability; case report

https://doi.org/10.11613/BM.2017.045

Biochemia Medica introduces new section: Pre-analytical mysteries

Ana-Maria Simundic, Janne Cadamuro, Michael Cornes

Pre-analytical mysteries, Volume 27, June, Issue 2

https://doi.org/10.11613/BM.2017.044

The alcohol used for cleansing the venipuncture site does not jeopardize blood and plasma alcohol measurement with head-space gas chromatography and an enzymatic assay

Giuseppe Lippi, Ana-Maria Simundic, Giacomo Musile, Elisa Danese, Gianluca Salvagno, Franco Tagliaro

Original papers, Volume 27, June, Issue 2

KEYWORDS: laboratory testing; diagnostics; alcohol; errors; pre-analytical phase

https://doi.org/10.11613/BM.2017.041

Labile glycated haemoglobin and carbamylated haemoglobin are still critical points for HbA measurement

Aurore Desmons, Stéphane Jaisson, Nathalie Leroy, Philippe Gillery, Emmanuelle Guillard

Original papers, Volume 27, June, Issue 2

KEYWORDS: carbamylated haemoglobin; labile glycated haemoglobin; HbA; analytical interference

https://doi.org/10.11613/BM.2017.039

Does recreational scuba diving have clinically significant effect on routine haematological parameters?

Antonija Perovic, Nora Nikolac, Marina Njire Braticevic, Ana Milcic, Sandra Sobocanec, Tihomir Balog, Sanja Dabelic, Jerka Dumic

Original papers, Volume 27, June, Issue 2

KEYWORDS: diving; preanalytical phase; blood cell count; evaluation

https://doi.org/10.11613/BM.2017.035

Urinary free cortisol assessment by liquid chromatography tandem mass spectrometry: a case study of ion suppression due to unacquainted administration of piperacillin

Elisa Danese, Gian Luca Salvagno, Alessandra Guzzo, Samuele Scurati, Cristiano Fava, Giuseppe Lippi

Pre-analytical Mysteries, Volume 27, October, Issue 3

KEYWORDS: urinary free cortisol; ion suppression; pre-analytical phase; piperacillin; mass spectrometry

https://doi.org/10.11613/BM.2017.031001

The new Greiner FC-Mix tubes equal the old Terumo ones and are useful as glucose stabilizer after prolonged storage of samples

Graziella Bonetti, Mariarosa Carta

Short Communications, Volume 27, October, Issue 3

KEYWORDS: diabetes; glucose; acidification; pre-analytical phase

https://doi.org/10.11613/BM.2017.030901

Analytical evaluation of a fully automated immunoassay for faecal calprotectin in a paediatric setting

Britta Noebauer, Lejla Ramic, Andrea Konstantin, Christina Zachbauer, Elisa Einwallner

Original Papers, Volume 27, October, Issue 3

KEYWORDS: calprotectin; faeces; particle-enhanced turbidimetric immunoassay (PETIA); inflammatory bowel disease

https://doi.org/10.11613/BM.2017.030710

National survey on current situation of critical value reporting in 973 laboratories in China

Yang Fei, Haijian Zhao, Wei Wang, Falin He, Kun Zhong, Shuai Yuan, Zhiguo Wang

Original Papers, Volume 27, October, Issue 3

KEYWORDS: critical value; quality indicators; extra-analytical phase

https://doi.org/10.11613/BM.2017.030707

Minimum requirements for the estimation of measurement uncertainty: Recommendations of the joint Working group for uncertainty of measurement of the CSMBLM and CCMB

Ivana Ćelap, Ines Vukasović, Gordana Juričić, Ana-Maria Šimundić

Review, Volume 27, October, Issue 3

KEYWORDS: measurement uncertainty; recommendations; harmonization; analytical phase

https://doi.org/10.11613/BM.2017.030502

Concerning the vitamin D reference range: pre-analytical and analytical variability of vitamin D measurement

Davide Ferrari, Giovanni Lombardi, Giuseppe Banfi

Review, Volume 27, October, Issue 3

KEYWORDS: vitamin D; biological variability; analytical variability; standardization; DEQAS

https://doi.org/10.11613/BM.2017.030501

Pneumatic tube system transport does not alter platelet function in optical and whole blood aggregometry, prothrombin time, activated partial thromboplastin time, platelet count and fibrinogen in patients on anti-platelet drug therapy

Dietmar Enko, Harald Mangge, Andreas Münch, Tobias Niedrist, Elisabeth Mahla, Helfried Metzler, Florian Prüller

Original Papers, Volume 27, February, Issue 1

KEYWORDS: platelets; platelet aggregation; platelet function tests; clinical laboratory services; preanalytical phase

https://doi.org/10.11613/BM.2017.023

Analytical robustness of nine common assays: frequency of outliers and extreme differences identified by a large number of duplicate measurements

Stefanie Neubig, Anne Grotevendt, Anders Kallner, Matthias Nauck, Astrid Petersmann

Original Papers, Volume 27, February, Issue 1

KEYWORDS: clinical chemistry tests; humans; reproducibility of results; analytical quality; quality control

https://doi.org/10.11613/BM.2017.021

Preanalytical investigations of phlebotomy: methodological aspects, pitfalls and recommendations

Cristiano Ialongo, Sergio Bernardini

Review, Volume 27, February, Issue 1

KEYWORDS: phlebotomy; preanalytical phase; statistical data analysis; methods

https://doi.org/10.11613/BM.2017.020

External quality assessment of medical laboratories in Croatia: preliminary evaluation of post-analytical laboratory testing

Jasna Lenicek Krleza, Adrijana Dorotic, Ana Grzunov

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: post-analytical phase; standardization; external quality assessment; questionnaire

https://doi.org/10.11613/BM.2017.018

Preanalytical external quality assessment of the Croatian Society of Medical Biochemistry and Laboratory Medicine and CROQALM: finding undetected weak spots

Nora Nikolac, Jasna Lenicek Krleza, Ana-Maria Simundic

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: preanalytical phase; external quality assessment; laboratory error

https://doi.org/10.11613/BM.2017.017

Timeliness “at a glance”: assessing the turnaround time through the six sigma metrics

Cristiano Ialongo, Sergio Bernardini

Original papers, Volume 26, February, Issue 1

KEYWORDS: turnaround time; statistical data analysis; quality control; healthcare quality indicator; postanalytical phase

https://doi.org/10.11613/BM.2016.010

The knowledge and understanding of preanalytical phase among biomedicine students at the University of Zagreb

Lora Dukic, Anja Jokic, Josipa Kules, Daria Pasalic

Original papers, Volume 26, February, Issue 1

KEYWORDS: survey; education; preanalytical phase

https://doi.org/10.11613/BM.2016.009

Evaluation of the appropriate time period between sampling and analyzing for automated urinalysis

Ramona C. Dolscheid-Pommerich, Ute Klarmann-Schulz, Rupert Conrad, Birgit Stoffel-Wagner, Berndt Zur

Original papers, Volume 26, February, Issue 1

KEYWORDS: urinalysis; automation; analytical sample preparation methods; flow cytometry; specimen handling

https://doi.org/10.11613/BM.2016.008

Unnecessary repeated total cholesterol tests in biochemistry laboratory

Suleyman Demir, Nergiz Zorbozan, Elif Basak

Original papers, Volume 26, February, Issue 1

KEYWORDS: unnecessary repeated cholesterol test; cholesterol retest interval; reference change value; laboratory costs; preanalytical phase; test requesting

https://doi.org/10.11613/BM.2016.007

Effectiveness of citrate buffer-fluoride mixture in Terumo tubes as an inhibitor of glycolysis

Graziella Bonetti, Mariarosa Carta, Martina Montagnana, Claudia Lo Cascio, Anna Rita Bonfigli, Andrea Mosca, Roberto Testa

Original papers, Volume 26, February, Issue 1

KEYWORDS: glucose; pre-analytical phase; sodium fluoride; citrate acidification; stability

https://doi.org/10.11613/BM.2016.006

Failure to review STAT clinical laboratory requests and its economical impact

Enrique Rodriguez-Borja, Celia Villalba-Martinez, Esther Barba-Serrano, Arturo Carratala-Calvo

Original papers, Volume 26, February, Issue 1

KEYWORDS: quality indicators; health care; extra-analytical phase; total quality management; clinical laboratory information systems

https://doi.org/10.11613/BM.2016.005

The effect of extremely high glucose concentrations on 21 routine chemistry and thyroid Abbott assays: interference study

Serap Çuhadar, Mehmet Köseoğlu, Yasemin Çinpolat, Güler Buğdaycı, Murat Usta, Tuna Semerci

Original papers, Volume 26, February, Issue 1

KEYWORDS: assay interference; glucose interference; preanalytical phase; creatinine; Jaffe kinetic assay; thyroid function tests

https://doi.org/10.11613/BM.2016.004

Abnormal gel flotation caused by contrast media during adrenal vein sampling

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Matteo Gelati, Antonella Bassi, Alberto Contro, Francesca Pizzolo, Gian Cesare Guidi

Case Report, Volume 26, October, Issue 3

KEYWORDS: preanalytical phase; blood specimen collection; contrast media; gels; phlebotomy

https://doi.org/10.11613/BM.2016.047

Indications for laboratory tests in primary care: assessment of the most frequent indications and requests with blank clinical information

Maria Salinas, Maite López-Garrigós, Emilio Flores, Maria Leiva-Salinas, Patricia Esteban, Miguel Ahumada, Carlos Leiva-Salinas

Short communication, Volume 26, October, Issue 3

KEYWORDS: clinical laboratory; pre-analytical phase; primary care; quality indicators; test request

https://doi.org/10.11613/BM.2016.045

A comparative evaluation of the analytical performances of Capillarys 2 Flex Piercing, Tosoh HLC-723 G8, Premier Hb9210, and Roche Cobas c501 Tina-quant Gen 2 analyzers for HbA determination

Xiaobin Wu, Yan Chao, Zemin Wan, Yunxiu Wang, Yan Ma, Peifeng Ke, Xinzhong Wu, Jianhua Xu, Junhua Zhuang, Xianzhang Huang

Original Papers, Volume 26, October, Issue 3

KEYWORDS: Haemoglobin A; capillary electrophoresis (CE); high-performance liquid chromatography (HPLC); affinity chromatography; immunoassay

https://doi.org/10.11613/BM.2016.039

The influence of sample freezing at – 80 °C for 2–12 weeks on glycated haemoglobin (HbA) concentration assayed by HPLC method on Bio-Rad D-10 auto analyzer

Katarzyna Bergmann, Grazyna Sypniewska

Original Papers, Volume 26, October, Issue 3

KEYWORDS: glycated haemoglobin; diabetes; sample storage; high performance liquid chromatography; preanalytical phase

https://doi.org/10.11613/BM.2016.038

Continuous quality control of the blood sampling procedure using a structured observation scheme

Tine Lindberg Seemann, Mads Nybo

Original papers, Volume 26, October, Issue 3

KEYWORDS: observation; phlebotomy; preanalytical phase; quality control

https://doi.org/10.11613/BM.2016.037

Phlebotomy, a bridge between laboratory and patient

Cristiano Ialongo, Sergio Bernardini

Review, Volume 26, February, Issue 1

KEYWORDS: phlebotomy; venipuncture; laboratory testing; preanalytical phase; preanalytical variability; patient safety; evidence based medicine

https://doi.org/10.11613/BM.2016.002

Automatic laboratory-based strategy to improve the diagnosis of type 2 diabetes in primary care

Maria Salinas, Maite López-Garrigós, Emilio Flores, Maria Leiva-Salinas, Javier Lugo, Francisco J Pomares, Alberto Asencio, Miguel Ahumada, Carlos Leiva-Salinas

Original papers, Volume 26, February, Issue 1

KEYWORDS: type 2 diabetes; HbA1c; diagnosis; preanalytical phase; test request appropriateness; costs; cost analysis

https://doi.org/10.11613/BM.2016.013

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Giuseppe Lippi, Patrizia Bonelli, Laura Bonfanti, Gianfranco Crevellin

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; hemolysis; blood specimen collection; catheter; emergency department

https://doi.org/10.11613/BM.2015.008

Comparison of blood ethanol stabilities in different storage periods

Fatma Emel Kocak, Ozben Ozden Isiklar, Havva Kocak, Ayfer Meral

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; ethanol; stability; storage temperature

https://doi.org/10.11613/BM.2015.006

The misuse and abuse of statistics in biomedical research

Matthew S. Thiese, Zachary C. Arnold, Skyler D. Walker

Lessons in biostatistics, Volume 25, February, Issue 1

KEYWORDS: a priori; analytical plan; statistical methods; disclosure; transparency; biostatistics

https://doi.org/10.11613/BM.2015.001

Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator

Maria Salinas, Maite López-Garrigós, Emilio Flores, Ana Santo-Quiles, Mercedes Gutierrez, Javier Lugo, Rosa Lillo, Carlos Leiva-Salinas

Original papers, Volume 25, February, Issue 1

KEYWORDS: Preanalytical phase; errors in laboratory medicine; balanced scorecard; patient safety

https://doi.org/10.11613/BM.2015.005

Larger differences in utilization of rarely requested tests in primary care in Spain

Maria Salinas, Maite López-Garrigós, Emilio Flores, Joaquín Uris, Carlos Leiva-Salinas

Original papers, Volume 25, October, Issue 3

KEYWORDS: primary care; laboratory proficiency testing; clinical laboratory services; test requesting; preanalytical phase

https://doi.org/10.11613/BM.2015.041

Confidence level in venipuncture and knowledge on causes of in vitro hemolysis among healthcare professionals

Dragana Milutinović, Ilija Andrijević, Milijana Ličina, Ljiljana Andrijević

Original papers, Volume 25, October, Issue 3

KEYWORDS: hemolysis; patient safety; phlebotomy; medical staff; questionnaire; preanalytical phase

https://doi.org/10.11613/BM.2015.040

Hemolysis from a nurses’ standpoint – survey from four Croatian hospitals

Adrijana Dorotić, Dragana Antončić, Vanja Radišić Biljak, Dara Nedić, Andjelo Beletić

Original papers, Volume 25, October, Issue 3

KEYWORDS: hemolysis; nurses; survey; preanalytical phase

https://doi.org/10.11613/BM.2015.039

Specimen rejection in laboratory medicine: Necessary for patient safety?

Zeliha Gunnur Dikmen, Asli Pinar, Filiz Akbiyik

Original papers, Volume 25, October, Issue 3

KEYWORDS: clinical laboratory services; total quality management; patient safety; preanalytical phase; preanalytical error

https://doi.org/10.11613/BM.2015.037

Capillary blood sampling: national recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Jasna Lenicek Krleza, Adrijana Dorotic, Ana Grzunov, Miljenka Maradin

Review Article, Volume 25, October, Issue 3

KEYWORDS: recommendations; capillary blood; blood specimen collection; standardization; preanalytical phase

https://doi.org/10.11613/BM.2015.034

How well are pregnant women in Croatia informed about the oral glucose tolerance test?

Patricija Bankovic Radovanovic, Marija Kocijancic

Research Article, Volume 25, June, Issue 2

KEYWORDS: preanalytical phase; oral glucose tolerance test; survey; patient education; gestational diabetes

https://doi.org/10.11613/BM.2015.023

Plasma centrifugation does not influence thrombin-antithrombin and plasmin-antiplasmin levels but determines platelet microparticles count

Ewa Stępień, Krzysztof Gruszczyński, Przemysław Kapusta, Artur Kowalik, Iwona Wybrańska

Research Article, Volume 25, June, Issue 2

KEYWORDS: cell-derived microparticles; blood coagulation tests; centrifugation; preanalytical phase

https://doi.org/10.11613/BM.2015.022

Croatian survey on critical results reporting

Lara Milevoj Kopcinovic, Jasenka Trifunović, Tihana Pavosevic, Nora Nikolac

Research Article, Volume 25, June, Issue 2

KEYWORDS: critical results; laboratory testing; quality indicators; survey; post-analytical phase

https://doi.org/10.11613/BM.2015.019

Preanalytical requirements of urinalysis

Joris Delanghe, Marijn Speeckaert

Review, Volume 24, February, Issue 1

KEYWORDS: flow cytometry; preservatives; sample preparation; urinalysis

https://doi.org/10.11613/BM.2014.011

Interference of medical contrast media on laboratory testing

Giuseppe Lippi, Massimo Daves, Camilla Mattiuzzi

Review, Volume 24, February, Issue 1

KEYWORDS: errors; analytical interference; contrast media; contrast agents; gadolinium

https://doi.org/10.11613/BM.2014.010

Physical activity - an important preanalytical variable

Fabian Sanchis-Gomar, Giuseppe Lippi

Review, Volume 24, February, Issue 1

KEYWORDS: biomarkers; training; plasma volume; metabolism; cellular damage

https://doi.org/10.11613/BM.2014.009

Preanalytical Phase – an updated review of the current evidence

Ana-Maria Simundic

Editorial, Volume 24, February, Issue 1

https://doi.org/10.11613/BM.2014.001

Lipemia: causes, interference mechanisms, detection and management

Nora Nikolac

Review, Volume 24, February, Issue 1

KEYWORDS: lipemia interference; laboratory error; preanalytical phase; interference testing; biological variation

https://doi.org/10.11613/BM.2014.008

Clinical biochemistry laboratory rejection rates due to various types of preanalytical errors

Aysenur Atay, Leyla Demir, Serap Cuhadar, Gulcan Saglam, Hulya Unal, Saliha Aksun, Banu Arslan, Asuman Ozkan, Recep Sutcu

Original papers, Volume 24, October, Issue 3

KEYWORDS: preanalytical error; quality indicator; specimen rejection

https://doi.org/10.11613/BM.2014.040

Evaluation of the BD Vacutainer® RST blood collection tube for routine chemistry analytes:clinical significance of differences and stability study

Marija Kocijancic, Jelena Cargonja, Alma Delic-Knezevic

Original papers, Volume 24, October, Issue 3

KEYWORDS: preanalytical phase; blood specimen collection; serum; test tube; evaluation

https://doi.org/10.11613/BM.2014.039

Contamination of lithium heparin blood by K2-ethylenediaminetetraacetic acid (EDTA): an experimental evaluation

Gabriel Lima-Oliveira, Gian Luca Salvagno, Elisa Danese, Giorgio Brocco, Gian Cesare Guidi, Giuseppe Lippi

Original papers, Volume 24, October, Issue 3

KEYWORDS: contamination; EDTA; patient safety; preanalytical variability; total quality management; preanalytical phase

https://doi.org/10.11613/BM.2014.038

Interferences from blood collection tube components on clinical chemistry assays

Raffick A.R. Bowen, Alan T. Remaley

Review, Volume 24, February, Issue 1

KEYWORDS: blood collection devices; blood collection sample tube; clinical assays; clinical chemistry; interference; pre-analytical; surfactant

https://doi.org/10.11613/BM.2014.006

Validation of an immunoassay to measure plasminogen-activator inhibitor-1 concentrations in human saliva

Xi Zhang, Goce Dimeski, Chamindie Punyadeera

Original papers, Volume 24, June, Issue 2

KEYWORDS: plasminogen activator inhibitor 1; saliva; immunoassay; cardiovascular diseases; analytical validation

https://doi.org/10.11613/BM.2014.028

History of the preanalytical phase: a personal view

Walter G. Guder

Review, Volume 24, February, Issue 1

KEYWORDS: influence factors; interference factors; preanalytical factors; amylase in urine; haemolytic samples; anticoagulants; blood collection tubes; centrifugation

https://doi.org/10.11613/BM.2014.005

Pre-analytical errors management in the clinical laboratory: a five-year study

Angeles Giménez-Marín, Francisco Rivas-Ruiz, Maria del Mar Pérez-Hidalgo, Pedro Molina-Mendoza

Original papers, Volume 24, June, Issue 2

KEYWORDS: total quality management; quality indicators; health care; laboratories; patient safety

https://doi.org/10.11613/BM.2014.027

Abnormal gel flotation in a patient with apperant pneumonia diagnosis: a case report

Fethullah Gerin, Dilber Coban Ramazan, Ozgur Baykan, Onder Sirikci, Goncagul Haklar

Case report, Volume 24, February, Issue 1

KEYWORDS: separator gel; preanalytical phase; blood collection tube; floating gel; hyperproteinemia

https://doi.org/10.11613/BM.2014.021

How to conduct External Quality Assessment Schemes for the pre-analytical phase?

Gunn B.B. Kristensen, Kristin Moberg Aakre, Ann Helen Kristoffersen, Sverre Sandberg

Review, Volume 24, February, Issue 1

KEYWORDS: quality assurance; health care; pre-analytical; quality indicators; health care; external quality assessment

https://doi.org/10.11613/BM.2014.013

Harmonization of pre-analytical quality indicators

Mario Plebani, Laura Sciacovelli, Ada Aita, Maria Laura Chiozza

Review, Volume 24, February, Issue 1

KEYWORDS: harmonization; pre-analytical-phase; quality indicators; patient safety; clinical laboratories

https://doi.org/10.11613/BM.2014.012

2nd EFLM-BD European Conference on Preanalytical Phase: Preanalytical quality improvement – in quality we trust, Zagreb, March 1-2, 2013

Symposium abstracts, Volume 23, February, Issue 1

https://doi.org/10.11613/BM.2013.015

The effect of storage time and freeze-thaw cycles on the stability of serum samples

Serap Cuhadar, Mehmet Koseoglu, Aysenur Atay, Ahmet Dirican

Original papers, Volume 23, February, Issue 1

KEYWORDS: preanalytical phase; serum; stability; storage; temperature

https://doi.org/10.11613/BM.2013.009

Evaluation of sample hemolysis in blood collected by S-Monovette® using vacuum or aspiration mode

Giuseppe Lippi, Paola Avanzini, Roberta Musa, Franca Sandei, Rosalia Aloe, Gianfranco Cervellin

Original papers, Volume 23, February, Issue 1

KEYWORDS: hemolysis; hemolyzed specimens; preanalytical variability; blood collection tube; blood drawing

https://doi.org/10.11613/BM.2013.008

Are patients well informed about the fasting requirements for laboratory blood testing?

Sanja Kackov, Ana-Maria Simundic, Ani Gatti-Drnic

Original papers, Volume 23, October, Issue 3

KEYWORDS: pre-analytical variability; fasting; patient education; quality indicators; self report questionnaires

https://doi.org/10.11613/BM.2013.040

Effect of sample type, centrifugation and storage conditions on vitamin D concentration

Ayfer Colak, Burak Toprak, Nese Dogan, Fusun Ustuner

Original papers, Volume 23, October, Issue 3

KEYWORDS: centrifugation; temperature; stability; vitamin D; preanalytical phase

https://doi.org/10.11613/BM.2013.039

Low level of adherence to instructions for 24-hour urine collection among hospital outpatients

Marijana Miler, Ana-Maria Šimundić

Original papers, Volume 23, October, Issue 3

KEYWORDS: data collection; preanalytical errors; questionnaires; urine specimen collection

https://doi.org/10.11613/BM.2013.038

The effective reduction of tourniquet application time after minor modification of the CLSI H03-A6 blood collection procedure

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 23, October, Issue 3

KEYWORDS: venous stasis; preanalytical phase; tourniquets; phlebotomy; practice guidelines

https://doi.org/10.11613/BM.2013.037

Reduction of gross hemolysis in catheter-drawn blood using Greiner Holdex® tube holder

Giuseppe Lippi, Paola Avanzini, Rosalia Aloe, Gianfranco Cervellin

Original papers, Volume 23, October, Issue 3

KEYWORDS: preanalytical variability; hemolysis; sample quality; intravenous line

https://doi.org/10.11613/BM.2013.036

Exhaled breath condensate – from an analytical point of view

Slavica Dodig, Ivana Čepelak

Review, Volume 23, October, Issue 3

KEYWORDS: exhaled breath condensate; analysis; preanalytical phase; respiratory diseases

https://doi.org/10.11613/BM.2013.034

Croatian Society of Medical Biochemistry and Laboratory Medicine: national recommendations for venous blood sampling

Nora Nikolac, Vesna Šupak-Smolčić, Ana-Maria Šimundić, Ivana Ćelap

Review, Volume 23, October, Issue 3

KEYWORDS: phlebotomy; venous blood; recommendations; health planning; laboratory errors; preanalytical phase

https://doi.org/10.11613/BM.2013.031

Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Case report, Volume 23, June, Issue 2

KEYWORDS: clinical laboratory techniques; preanalytical phase; laboratory variability; blood specimen collection; EDTA contamination carryover

https://doi.org/10.11613/BM.2013.026

Avoidance to wipe alcohol before venipuncture is not a source of spurious hemolysis

Gian Luca Salvagno, Elisa Danese, Gabriel Lima-Oliveira, Gian Cesare Guidi, Giuseppe Lippi

Original papers, Volume 23, June, Issue 2

KEYWORDS: preanalytical variability; hemolysis; alcohol; practice guideline

https://doi.org/10.11613/BM.2013.023

Critical review and meta-analysis of spurious hemolysis in blood samples collected from intravenous catheters

Giuseppe Lippi, Gianfranco Cervellin, Camilla Mattiuzzi

Original papers, Volume 23, June, Issue 2

KEYWORDS: hemolysis; preanalytical variability; catheters; meta-analysis

https://doi.org/10.11613/BM.2013.022

Preanalytical considerations in blood gas analysis

Geoffrey Baird

Review, Volume 23, February, Issue 1

KEYWORDS: blood gas analysis; preanalytical error; laboratory error; pO2; pCO2; pH

https://doi.org/10.11613/BM.2013.005

Impact of the phlebotomy training based on CLSI/NCCLS H03-A6 – procedures for the collection of diagnostic blood

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 22, October, Issue 3

KEYWORDS: phlebotomy; blood specimen collection; tourniquet application time; CLSI documents; pre-analytic variability; extra- analytical variability

https://doi.org/10.11613/BM.2012.036

Preanalytical management: serum vacuum tubes validation for routine clinical chemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 22, June, Issue 2

KEYWORDS: preanalytical variability; blood collection; serum samples; vacuum tubes; validation process

https://doi.org/10.11613/BM.2012.021

Preanalytical phase – a continuous challenge for laboratory professionals

Ana-Maria Simundic, Giuseppe Lippi

Editorial, Volume 22, June, Issue 2

KEYWORDS: preanalytical phase; errors; quality indicators; phlebotomy; blood sampling

https://doi.org/10.11613/BM.2012.017

Abstracts of the 1st EFCC-BD European Conference on Preanalytical Phase

Symposium abstracts, Volume 21, June, Issue 2

Effects of hemolysis interference on routine biochemistry parameters

Mehmet Koseoglu, Aysel Hur, Aysenur Atay, Serap Cuhadar

Original papers, Volume 21, February, Issue 1

KEYWORDS: hemolysis; preanalytical errors; interference; analytes.

https://doi.org/10.11613/BM.2011.015

Studies on in vitro hemolysis and utility of corrective formulas for reporting results on hemolyzed specimens

Giuseppe Lippi, Paola Avanzini, Fernan da Pavesi, Mirco Bardi, Luigi Ippolito, Rosalia Aloe, Emmanuel J Favaloro

Original papers, Volume 21, October, Issue 3

KEYWORDS: hemolysis; hemolyzed specimens; interference; preanalytical variability

https://doi.org/10.11613/BM.2011.040

Validation of methods performance for routine biochemistry analytes at Cobas 6000 analyzer series module c501

Vesna Supak Smolcic, Lidija Bilic-Zulle, Elizabeta Fisic

Original papers, Volume 21, June, Issue 2

KEYWORDS: validation study; chemistry techniques; analytical; Cobas 6000 analyzer; total error; Passing and Bablock regression

https://doi.org/10.11613/BM.2011.028

New ways to deal with known preanalytical issues: use of transilluminator instead of tourniquet for easing vein access and eliminating stasis on clinical biochemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Cristovão Luis Pitanguiera Manguera, Nairo M. Sumita, Geraldo Picheth, Gian Cesare Guidi, Marileia Scartezini

Original papers, Volume 21, June, Issue 2

KEYWORDS: phlebotomy and blood collection; pre analytical phase; quality management system in clinical laboratory; transillumination; venous stasis.

https://doi.org/10.11613/BM.2011.024

Development of a preanalytical errors recording software

Giuseppe Lippi, Patrizia Bonelli, Rossana Rossi, Mirco Bardi, Rosalia Aloe, Alberta Caleffi, Enrichetta Bonilauri

Original papers, Volume 20, February, Issue 1

KEYWORDS: errors; laboratory testing; computer program; informatics; extra-analytical phase

https://doi.org/10.11613/BM.2010.011

Self reported routines and procedures for the extra-analytical phase of laboratory practice in Croatia - cross-sectional survey study

Lidija Bilić-Zulle, Ana-Maria Simundic, Vesna Šupak Smolčić, Nora Nikolac, Lorena Honović

Original papers, Volume 20, February, Issue 1

KEYWORDS: clinical chemistry tests; extra-analytical phase; quality of health care; questionnaire

https://doi.org/10.11613/BM.2010.008

Total quality in laboratory diagnostics. It's time to think outside the box

Giuseppe Lippi, Ana-Maria Simundic

Editorial, Volume 20, February, Issue 1

KEYWORDS: patient safety; laboratory diagnostics; preanalytical phase; errors; quality

https://doi.org/10.11613/BM.2010.001

Analytical evaluation of the clinical chemistry analyzer Olympus AU2700 plus

Jasna Juricek, Lovorka Derek, Adriana Unic, Tihana Serdar, Domagoj Marijancevic, Marcela Zivkovic, Zeljko Romic

Original papers, Volume 20, October, Issue 3

KEYWORDS: Olympus AU2700 plus; analytical evaluation; imprecision; inaccuracy; Passing Bablok regression analysis

https://doi.org/10.11613/BM.2010.043

Short-term increases of plasma cardiac troponin I are better evaluated by comparison with the reference change value

Giovanni Introcaso, Monica Raggi, Tiziana D’Errico, Annalisa Cavallero

Original papers, Volume 20, October, Issue 3

KEYWORDS: cardiac troponin-I; reference change value; analytical imprecision; acute coronary syndrome

https://doi.org/10.11613/BM.2010.042

Analytical validation of therapeutic drug monitoring (TDM) on AxSYM Abbott analyzer

Nora Nikolac, Ana-Maria Simundic, Nada Vukelic, Dalja Papic Futac, Nada Vrkic

Original papers, Volume 20, June, Issue 2

KEYWORDS: analytical validation; measurement uncertainty; valproic acid; phenobarbital; carbamazepine; theophylline

https://doi.org/10.11613/BM.2010.032

Total quality in laboratory diagnostics: the role of commercial companies

Ana K. Stankovic, Jeffrey Silvetri2, Michael Mails, Carmen Najork

Special issue, Volume 20, June, Issue 2

KEYWORDS: preanalytical systems; in vitro diagnostic devices; laboratory instrument; reagent; quality

https://doi.org/10.11613/BM.2010.025

Quality in the extra-analytical phases of urinalysis

Alberta Caleffi, Fabio Manoni, Maria Grazia Alessio, Cosimo Ottomano, Giuseppe Lippi

Special issue, Volume 20, June, Issue 2

KEYWORDS: urine; urinalysis; quality; prenalytical phase

https://doi.org/10.11613/BM.2010.022

Notification of critical values

Mario Plebani, Elisa Piva

Special issue, Volume 20, June, Issue 2

KEYWORDS: critical values; notification of critical values; clinical laboratories; post-analytical phase; errors in laboratory medicine

https://doi.org/10.11613/BM.2010.021

The role of the External Quality Assessment

Laura Sciacovelli, Sandra Secchiero, Lorena Zardo, Mario Plebani

Special issue, Volume 20, June, Issue 2

KEYWORDS: External Quality Assessment; proficiency testing; laboratory performance; analytical quality; analytical quality control

https://doi.org/10.11613/BM.2010.019

Hemolysis detection and management of hemolyzed specimens

Ana-Maria Simundic, Elizabeta Topic, Nora Nikolac, Giuseppe Lippi

Special issue, Volume 20, June, Issue 2

KEYWORDS: hemolysis; extra-analytical quality; errors; laboratory testing; interference

https://doi.org/10.11613/BM.2010.018

Quality in the analytical phase

Oswald Sonntag

Special issue, Volume 20, June, Issue 2

KEYWORDS: analytical errors; patient safety; clinical laboratory; quality control; drug interference; calibration; paraprotein; reference interval

https://doi.org/10.11613/BM.2010.017

Quality and diagnostic perspectives in laboratory diagnostics

Mathias M. Müller

Special issue, Volume 20, June, Issue 2

KEYWORDS: laboratory medicine; diagnostic process; pre-analytical phase; post-analytical phase

https://doi.org/10.11613/BM.2010.016

Analytical performance of the Gem® PremierTM 4000 – a comparison study

Snježana Hrabrić Vlah, Štefica Dvornik, Dino Grdović

Original papers, Volume 19, June, Issue 2

KEYWORDS: point of care testing; Gem® PremierTM 4000; hemoglobin

https://doi.org/10.11613/BM.2009.018

Accu Chek Compact Plus blood glucometer evaluation

Jelena Kozar, Ana-Maria Simundic, Nora Nikolac, Marijana Žirović, Elizabeta Topić

Original papers, Volume 18, October, Issue 3

KEYWORDS: accuracy; precision; analytical evaluation; self monitoring blood glucose device; Bland-Altman; Clarke Error Grid analysis

https://doi.org/10.11613/BM.2008.032

Laboratory errors: How to improve pre- and post-analytical phases?

Mario Plebani

Editorial, Volume 17, June, Issue 1

https://doi.org/10.11613/BM.2007.001

Analytical properties of the GEM premier 3000 analyzer evaluated

Nada Vukelić, Dalja Papić Futač, Elizabeta Topić

Original papers, Volume 17, December, Issue 2

KEYWORDS: point of care testing; acid-base balance parameters; electrolytes; metabolites

https://doi.org/10.11613/BM.2007.023

Analytical evaluation of P1NP assay, a biochemical marker of bone turnover

Marko Marcius, Nada Vrkić, Biserka Getaldić-Švarc

Original papers, Volume 16, December, Issue 2

KEYWORDS: analytical evaluation; amino terminal propeptide type I procollagen; P1NP; electrochemiluminescent immunoassay; bone markers

https://doi.org/10.11613/BM.2006.017

Assessment of analytical properties of the Randox full range assay for determination of C-reactive protein concentration in preterm infants and newborns

Nada Vukelić, Ines Vukasović, Elizabeta Topić

Original papers, Volume 16, December, Issue 2

KEYWORDS: C-reactive protein; sepsis; preterm infants; newborns

https://doi.org/10.11613/BM.2006.016