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A case of alkaptonuria presenting with unexplained dark-stained diapers and spurious hyperoxaluria and proteinuria due to homogentisic acid interference

Thibault Vanhove, Margo Aertgeerts, Peter Witters, Daisy Rymen, Detlef Böckenhauer, Glynis Frans, Pieter Vermeersch

Preanalytical mysteries, Volume 34, October, Issue 3

KEYWORDS: preanalytical phase; interference; homogentisic acid; dark-stained urine; alkaptonuria; inborn errors of metabolism; case report

https://doi.org/10.11613/BM.2024.031002

Glucose inhibitor tubes in Croatian laboratories: are we doing well?

Alen Vrtarić, Nora Nikolac Gabaj, Ivana Ćelap

Short communications, Volume 34, October, Issue 3

KEYWORDS: preanalytical phase; glucose; glucose inhibitor; anticoagulants; citrate

https://doi.org/10.11613/BM.2024.030901

Short- and long-term stability of synovial fluid calprotectin

Helena Čičak, Stjepan Bulat, Joško Jeličić, Alan Ivković, Ksenija Maštrović Radončić, Vanja Radišić Biljak, Lora Dukić, Ana-Maria Šimundić

Original articles, Volume 34, October, Issue 3

KEYWORDS: calprotectin; preanalytical phase; stability; synovial fluid

https://doi.org/10.11613/BM.2024.030704

Stability of adrenocorticotropic hormone in whole blood samples: effects of storage conditions

François Fraissinet, Hélène Girot, André Gillibert, Anaïs Melin, Julie Fettig, Valéry Brunel

Original articles, Volume 34, October, Issue 3

KEYWORDS: adrenocorticotropic hormone; hemolysis; preanalytical phase; specimen stability; whole blood

https://doi.org/10.11613/BM.2024.030702

A survey on the practice of phlebotomy in Lithuania and adherence to the EFLM-COLABIOCLI recommendations: continuous training and clear standard operating procedures as tools for better quality

Ricardas Stonys, Dalius Vitkus

Original articles, Volume 34, June, Issue 2

KEYWORDS: preanalytical phase; phlebotomy; blood specimen collection; healthcare quality assurance

https://doi.org/10.11613/BM.2024.020702

Comparison of lipemia interference created with native lipemic material and intravenous lipid emulsion in emergency laboratory tests

Emel Çolak Samsum, Hatice Sürer, Serkan Bolat, Mehmet Şeneş, Doğan Yücel

Original articles, Volume 34, June, Issue 2

KEYWORDS: lipemia; intravenous lipid emulsions; interference; clinical chemistry tests; preanalytical phase

https://doi.org/10.11613/BM.2024.020701

Preanalytical, analytical and postanalytical considerations in circulating microRNAs measurement

Mustapha Zendjabil

Reviews, Volume 34, June, Issue 2

KEYWORDS: microRNAs; preanalytical phase; blood collection; biomarkers; liquid biopsy

https://doi.org/10.11613/BM.2024.020501

Blood alcohol concentration in the clinical laboratory: a narrative review of the preanalytical phase in diagnostic and forensic testing

Cristiano Ialongo

Reviews, Volume 34, February, Issue 1

KEYWORDS: preanalytical phase; blood alcohol concentration; specimen handling; humans; substance abuse detection

https://doi.org/10.11613/BM.2024.010501

Changing the tide in vitamin D testing: An 8-year review of a demand management approach

Janne Cadamuro, Ursula Huber-Schönauer, Cornelia Mrazek, Lukas Hehenwarter, Ulrike Kipman, Thomas K. Felder, Christian Pirich

Letters to the editor, Volume 34, February, Issue 1

KEYWORDS: demand management; preanalytical phase; laboratory order; vitamin D

https://doi.org/10.11613/BM.2024.010401

Fibrin clot interference in a human chorionic gonadotrophin assay causing a false Down syndrome screening result

Arzu Etem Akagac, Hatice Bozkurt Yavuz

Preanalytical mysteries, Volume 33, February, Issue 1

KEYWORDS: hCG; prenatal screening; fibrin; preanalytical phase; case report

https://doi.org/10.11613/BM.2023.011001

A case of discrepant laboratory results in samples obtained from a central venous catheter and peripheral veins: when solving a pre-analytical mystery could improve patient care

Mattia Carini, Moira Micheletti, Giovanni Martellosio, Elisa Caravaggi, Nicola Portesi, Giorgio Biasiotto, Monica Marini, Duilio Brugnoni, Federico Serana

Preanalytical mysteries, Volume 32, October, Issue 3

KEYWORDS: blood specimen collection; pre-analytical phase; medical error; central venous catheters; haematology

https://doi.org/10.11613/BM.2022.031001

Inter-rater reliability assessment for the new-born screening quality assurance

Leonor Guiñón, Anna Soler, Rosa María López, Sonia Pajares, José Manuel González de Aledo, Ana Argudo-Ramírez, José Luis Marín, Judit García-Villoria, Ángeles Sahuquillo, Luisa Alvarez

Short communication, Volume 32, October, Issue 3

KEYWORDS: accreditation; extra-analytical phase; new-born screening; quality control

https://doi.org/10.11613/BM.2022.030901

Evaluation of preanalytical and postanalytical phases in clinical biochemistry laboratory according to IFCC laboratory errors and patient safety specifications

Nergiz Zorbozan, Orçun Zorbozan

Original articles, Volume 32, October, Issue 3

KEYWORDS: total quality management; preanalytical phase; quality indicators; six sigma

https://doi.org/10.11613/BM.2022.030701

Post-collection acidification of spot urine sample is not needed before measurement of electrolytes

Tomáš Šálek, Pavel Musil, Marek Pšenčík, Vladimír Palička

Original articles, Volume 32, June, Issue 2

KEYWORDS: urolithiasis; calcium; magnesium; phosphorus; preanalytical phase

https://doi.org/10.11613/BM.2022.020702

Deviating glucose results in an international dual-center study. A root cause investigation

Janne Cadamuro, Peter Bergsten, Katharina Mörwald, Anders Forslund, Marie Dahlbom, Jonas Bergquist, Iris Ciba, Susanne M. Brunner, Jeanne Jabbour, Daniel Weghuber

Preanalytical mysteries, Volume 32, February, Issue 1

KEYWORDS: preanalytical phase; tube additive; PREDICT; blood collection tubes; preanalytical error

https://doi.org/10.11613/BM.2022.011001

Interpretative comments - need for harmonization? Results of the Croatian survey by the Working Group for Post-analytics

Vladimira Rimac, Sonja Podolar, Anja Jokic, Jelena Vlasic Tanaskovic, Lorena Honovic, Jasna Lenicek Krleza

Short communications, Volume 32, February, Issue 1

KEYWORDS: post-analytical phase; clinical laboratory; interpretative comments; questionnaire

https://doi.org/10.11613/BM.2022.010901

Review of current incidents and risk calculations used in the Royal College of Australasian Pathologists Key Incident Management and Monitoring Systems - a system that could be used by all Australasian medical laboratories, and easily adapted to worldwide use

Stephanie Gay, Belinda Pope, Tony Badrick, Michael Whiley

Original articles, Volume 32, February, Issue 1

KEYWORDS: extra-analytical phase; laboratory organisation and management; pre- and post-analytical incidents; risk matrix; quality assurance

https://doi.org/10.11613/BM.2022.010702

The concurrence of the current postanalytical phase management with the national recommendations: a survey of the Working Group for Postanalytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Anja Jokic, Vladimira Rimac, Jelena Vlasic Tanaskovic, Sonja Podolar, Lorena Honovic, Jasna Lenicek Krleza

Original articles, Volume 31, October, Issue 3

KEYWORDS: postanalytical phase; survey; clinical laboratory; critical results; quality indicators

https://doi.org/10.11613/BM.2021.030704

The missing slope: paradoxical shortening of activated partial thromboplastin time in a patient on unfractionated heparin therapy

Ivana Lapić, Ana Lončar Vrančić, Désirée Coen Herak, Dunja Rogić

Preanalytical Mysteries, Volume 31, June, Issue 2

KEYWORDS: pre-analytical phase; hemostasis; activated partial thromboplastin time; unfractionated heparin

https://doi.org/10.11613/BM.2021.021003

Delayed diagnosis and treatment of extreme hypertriglyceridemia due to rejection of a lipemic sample

Jan Van Elslande, Samira Hijjit, Katrien De Vusser, Michel Langlois, Björn Meijers, Ann Mertens, Bart Van der Schueren, Glynis Frans, Pieter Vermeersch

Preanalytical Mysteries, Volume 31, June, Issue 2

KEYWORDS: extra-analytical phase; hypertriglyceridemia; interferences; lipemia; lipoprotein metabolism

https://doi.org/10.11613/BM.2021.021002

The rise in preanalytical errors during COVID-19 pandemic

Tapasyapreeti Mukhopadhyay, Arulselvi Subramanian, Shivam Pandey, Nirupam Madaan, Anjan Trikha, Rajesh Malhotra

Original Articles, Volume 31, June, Issue 2

KEYWORDS: laboratory biosafety; preanalytical phase; quality indicators; SARS-CoV-2; total testing process

https://doi.org/10.11613/BM.2021.020710

Order of draw of blood samples affect potassium results without K-EDTA contamination during routine workflow

Şerif Ercan, Bahri Ramadan, Ozan Gerenli

Original Articles, Volume 31, June, Issue 2

KEYWORDS: EDTA contamination; order of draw; patient safety; phlebotomy; preanalytical phase; pseudohyperkalaemia

https://doi.org/10.11613/BM.2021.020704

A case of severe pseudohyperkalaemia due to muscle contraction

Jan Van Elslande, Toon Dominicus, Jaan Toelen, Glynis Frans, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, June, Issue 2

KEYWORDS: hyperkalaemia; pseudohyperkalaemia; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.021004

Dark brown serum and plasma samples: a case report

Lora Dukic, Nikolina Maric, Ana-Maria Simundic

Preanalytical mysteries, Volume 30, June, Issue 2

KEYWORDS: case report; critical care; extra-analytical phase; sample coloration

https://doi.org/10.11613/BM.2020.021002

Quality improvement project: Reducing non-conformities of the samples for haemostasis testing in a secondary healthcare centre through the nurses’ education in phlebotomy

Patricija Banković Radovanović

Original Articles, Volume 30, June, Issue 2

KEYWORDS: quality improvement; phlebotomy; education; pre-analytical phase

https://doi.org/10.11613/BM.2020.020708

Survey on request form content and result reporting in therapeutic drug monitoring service among laboratories in Czechia and Slovakia

Tomáš Šálek, Petr Schneiderka, Barbora Studená, Michaela Votroubková

Original Articles, Volume 30, June, Issue 2

KEYWORDS: drug monitoring; pharmacokinetics; preanalytical phase; clinical laboratory services; kidney function tests

https://doi.org/10.11613/BM.2020.020706

General position of Croatian medical biochemistry laboratories on autovalidation: survey of the Working Group for Post-analytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Vladimira Rimac, Anja Jokic, Sonja Podolar, Jelena Vlasic Tanaskovic, Lorena Honovic, Jasna Lenicek Krleza

Original papers, Volume 30, June, Issue 2

KEYWORDS: postanalytical phase; autovalidation; clinical laboratory; questionnaire

https://doi.org/10.11613/BM.2020.020702

Long-term stability of clinically relevant chemistry analytes in pleural and peritoneal fluid

Lara Milevoj Kopcinovic, Marija Brcic, Alen Vrtaric, Adriana Unic, Marija Bozovic, Nora Nikolac Gabaj, Marijana Miler, Jelena Culej

Original papers, Volume 30, June, Issue 2

KEYWORDS: stability; pleural effusion; peritoneal effusion; preanalytical phase

https://doi.org/10.11613/BM.2020.020701

Errors within the total laboratory testing process, from test selection to medical decision-making – A review of causes, consequences, surveillance and solutions

Cornelia Mrazek, Giuseppe Lippi, Martin H Keppel, Thomas K Felder, Hannes Oberkofler, Elisabeth Haschke-Becher, Janne Cadamuro

Review, Volume 30, June, Issue 2

KEYWORDS: total testing process; extra-analytical phase; quality indicators; laboratory medicine; patient safety

https://doi.org/10.11613/BM.2020.020502

The effect of jet-lag on serum concentrations of thyroid stimulating hormone and prolactin: A case report

Merve Sibel Gungoren, Deniz Ilhan Topcu, Cevdet Zungun

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: preanalytical phase; case report; jet-lag; thyroid stimulating hormone; prolactin

https://doi.org/10.11613/BM.2020.011003

Unexpected abnormal coagulation test results in a 2-year-old child: A case report

Patricija Banković Radovanović, Tanja Živković Mikulčić, Jasmina Simović Medica

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: case report; preanalytical phase; sample collection; coagulation

https://doi.org/10.11613/BM.2020.011002

High anion gap metabolic acidosis caused by D-lactate: mind the time of blood collection

Matthias Weemaes, Martin Hiele, Pieter Vermeersch

Preanalytical Mysteries, Volume 30, February, Issue 1

KEYWORDS: D-lactate; D-lactic acidosis; high anion gap acidosis; preanalytical phase; case report

https://doi.org/10.11613/BM.2020.011001

Six Sigma revisited: We need evidence to include a 1.5 SD shift in the extraanalytical phase of the total testing process

Abdurrahman Coskun, Cristiano Ialongo

Short Communication, Volume 30, February, Issue 1

KEYWORDS: extraanalytical phase; shift; Sigma metric; Six Sigma; total testing process

https://doi.org/10.11613/BM.2020.010901

Study of the preanalytical variables affecting the measurement of clinically relevant free-circulating microRNAs: focus on sample matrix, platelet depletion, and storage conditions

Martina Faraldi, Veronica Sansoni, Silvia Perego, Marta Gomarasca, Jakub Kortas, Ewa Ziemann, Giuseppe Banfi, Giovanni Lombardi

Original Articles, Volume 30, February, Issue 1

KEYWORDS: circulating microRNA; biomarkers; plasma; preanalytical phase

https://doi.org/10.11613/BM.2020.010703

Flushing of an intravenous catheter: a cause for unreliable laboratory results

Rutger C.C. Hengeveld, Maaike C. Gerards, Bianca E. Olofsen, Milan L. Ridderikhof, Victor F.H.A. Hakkenberg van Gaasbeek, Peter A. Leenhouts, Edmée C. van Dongen-Lases

Preanalytical Mysteries, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; phlebotomy; intravenous catheter

https://doi.org/10.11613/BM.2019.031001

Clinician’s opinion about critical risk results proposed by the Croatian Chamber of Medical Biochemists: a survey in one Croatian tertiary hospital

Pavica Šonjić, Ana Nikler, Dora Vuljanić, Lora Dukić, Ana-Maria Šimundić

Original Articles, Volume 29, October, Issue 3

KEYWORDS: critical results; survey; post-analytical phase; laboratory management

https://doi.org/10.11613/BM.2019.030711

Time-dependent variation of ionized calcium in serum samples

Antonija Perović, Marina Njire Bratičević

Original Articles, Volume 29, October, Issue 3

KEYWORDS: ionized calcium; serum; heparin; specimen handling; pre-analytical phase

https://doi.org/10.11613/BM.2019.030708

Effectiveness of minimum retesting intervals in managing repetitive laboratory testing: experience from a Croatian university hospital

Ivana Lapić, Dunja Rogić, Mirjana Fuček, Ružica Galović

Original Articles, Volume 29, October, Issue 3

KEYWORDS: evidence-based practice; clinical laboratory services; pre-analytical phase; cost analysis

https://doi.org/10.11613/BM.2019.030705

Assessment of the degree of adherence of medical laboratories to KDIGO 2012 guideline for evaluation and management of CKD in Czechia and Slovakia

Šálek Tomáš, Friedecký Bedřich, Kratochvíla Josef, Pelinková Květa, Budina Marek

Original Articles, Volume 29, October, Issue 3

KEYWORDS: creatinine; cystatin C; glomerular filtration; estimated glomerular filtration rate; post-analytical phase

https://doi.org/10.11613/BM.2019.030704

Preanalytical classical and alternative complement pathway activity loss

Koen O.A. Vercauteren, Stijn Lambrecht, Joris Delanghe

Original Articles, Volume 29, October, Issue 3

KEYWORDS: preanalytical phase; alternative and classical complement pathway; complement haemolytic activity assay; complement C3; complement C3d

https://doi.org/10.11613/BM.2019.030701

An abrupt rise of coagulation error messages on ACL TOP automated analysers

Bas Calcoen, Koen Desmet, Pieter Vermeersch

Preanalytical Mysteries, Volume 29, June, Issue 2

KEYWORDS: preanalytical phase; blood coagulation test; diagnostic error; blood specimen collection

https://doi.org/10.11613/BM.2019.021002

Evaluation of a commercial liquid-chromatography high-resolution mass-spectrometry method for the determination of hepcidin-25

Dietmar Enko, Sieglinde Zelzer, Günter Fauler, Markus Herrmann

Original articles, Volume 29, June, Issue 2

KEYWORDS: hepcidin-25; preanalytical phase; protein biomarker; liquid-chromatography high-resolution mass-spectrometry

https://doi.org/10.11613/BM.2019.020701

Post-analytical laboratory work: national recommendations from the Working Group for Post-analytics on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Jasna Lenicek Krleza, Lorena Honovic, Jelena Vlasic Tanaskovic, Sonja Podolar, Vladimira Rimac, Anja Jokic

Review, Volume 29, June, Issue 2

KEYWORDS: recommendations; post-analytical phase; clinical laboratory; harmonization; test report

https://doi.org/10.11613/BM.2019.020502

Plasma free DNA: Evaluation of temperature-associated storage effects observed for Roche Cell-Free DNA collection tubes

Dietmar Enko, Gabriele Halwachs-Baumann, Gernot Kriegshäuser

Short Communications, Volume 29, February, Issue 1

KEYWORDS: cell-free nucleic acids; pre-analytical phase; quality improvement

https://doi.org/10.11613/BM.2019.010904

Effects of different anticoagulants on glycated albumin quantification

Graziella Bonetti, Nicola Di Gaetano, Renata Paleari, Ferruccio Ceriotti

Short Communications, Volume 29, February, Issue 1

KEYWORDS: preanalytical phase; serum albumin; diabetes mellitus; anticoagulants

https://doi.org/10.11613/BM.2019.010901

Faecal calprotectin determination: impact of preanalytical sample treatment and stool consistency on within- and between-method variability

Gordana Juricic, Tina Brencic, Andrea Tesija-Kuna, Milena Njegovan, Lorena Honovic

Original Articles, Volume 29, February, Issue 1

KEYWORDS: calprotectin; preanalytical phase; inflammatory bowel disease; immunoassay

https://doi.org/10.11613/BM.2019.010707

Confidence interval for quantiles and percentiles

Cristiano Ialongo

Lessons in Biostatistics, Volume 29, February, Issue 1

KEYWORDS: biostatistics; statistical methods; confidence intervals; extra-analytical phase

https://doi.org/10.11613/BM.2019.010101

Biotin and high-sensitivity cardiac troponin T assay

Aurélien Schrapp, François Fraissinet, Charles Hervouet, Hélène Girot, Valéry Brunel

Short Communication, Volume 28, October, Issue 3

KEYWORDS: troponin T; biotin; multiple sclerosis; preanalytical phase

https://doi.org/10.11613/BM.2018.030901

Haematology specimen acceptability: a national survey in Chinese laboratories

Yuanyuan Ye, Wei Wang, Haijian Zhao, Falin He, Kun Zhong, Shuai Yuan, Yuxuan Du, Bingquan Chen, Zhiguo Wang

Original Papers, Volume 28, October, Issue 3

KEYWORDS: quality indicator; preanalytical phase; quality control; haematology; survey

https://doi.org/10.11613/BM.2018.030704

Utilization of a healthcare failure mode and effects analysis to identify error sources in the preanalytical phase in two tertiary hospital laboratories

Adolfo Romero, Juan Gómez-Salgado, Adolfo Romero-Arana, Carlos Ruiz-Frutos

Original Papers, Volume 28, June, Issue 2

KEYWORDS: preanalytical phase; Healthcare Failure Mode and Effects Analysis; quality assessment; errors

https://doi.org/10.11613/BM.2018.020713

Effect of different pre-analytical conditions on plasma lactate concentration

Ivana Rako, Ana Mlinaric, Monika Dozelencic, Gordana Fressl Juros, Dunja Rogic

Original Papers, Volume 28, June, Issue 2

KEYWORDS: plasma lactate; blood analysis; blood specimen collection; haemolysis; pre-analytical phase

https://doi.org/10.11613/BM.2018.020701

Elevated zinc concentrations in a 5 months old infant: A case report

Eva Rabing Brix Petersen, Sven Mortensen, Mads Nybo

Pre-analytical Mysteries, Volume 28, February, Issue 1

KEYWORDS: capillary blood sample; case report; pre-analytical phase; zinc

https://doi.org/10.11613/BM.2018.011001

Preanalytics of urine sediment examination: effect of relative centrifugal force, tube type, volume of sample and supernatant removal

Amalija Bunjevac, Nora Nikolac Gabaj, Marijana Miler, Anita Horvat

Original Papers, Volume 28, February, Issue 1

KEYWORDS: preanalytical phase; laboratory error; urinalysis; urine sediment

https://doi.org/10.11613/BM.2018.010707

Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey

Qian Cai, Yunxian Zhou, Dangan Yang

Original Papers, Volume 28, February, Issue 1

KEYWORDS: pre-analytical phase; venous blood sampling; knowledge; nurses; phlebotomy

https://doi.org/10.11613/BM.2018.010703

The alcohol used for cleansing the venipuncture site does not jeopardize blood and plasma alcohol measurement with head-space gas chromatography and an enzymatic assay

Giuseppe Lippi, Ana-Maria Simundic, Giacomo Musile, Elisa Danese, Gianluca Salvagno, Franco Tagliaro

Original papers, Volume 27, June, Issue 2

KEYWORDS: laboratory testing; diagnostics; alcohol; errors; pre-analytical phase

https://doi.org/10.11613/BM.2017.041

Does recreational scuba diving have clinically significant effect on routine haematological parameters?

Antonija Perovic, Nora Nikolac, Marina Njire Braticevic, Ana Milcic, Sandra Sobocanec, Tihomir Balog, Sanja Dabelic, Jerka Dumic

Original papers, Volume 27, June, Issue 2

KEYWORDS: diving; preanalytical phase; blood cell count; evaluation

https://doi.org/10.11613/BM.2017.035

Urinary free cortisol assessment by liquid chromatography tandem mass spectrometry: a case study of ion suppression due to unacquainted administration of piperacillin

Elisa Danese, Gian Luca Salvagno, Alessandra Guzzo, Samuele Scurati, Cristiano Fava, Giuseppe Lippi

Pre-analytical Mysteries, Volume 27, October, Issue 3

KEYWORDS: urinary free cortisol; ion suppression; pre-analytical phase; piperacillin; mass spectrometry

https://doi.org/10.11613/BM.2017.031001

The new Greiner FC-Mix tubes equal the old Terumo ones and are useful as glucose stabilizer after prolonged storage of samples

Graziella Bonetti, Mariarosa Carta

Short Communications, Volume 27, October, Issue 3

KEYWORDS: diabetes; glucose; acidification; pre-analytical phase

https://doi.org/10.11613/BM.2017.030901

National survey on current situation of critical value reporting in 973 laboratories in China

Yang Fei, Haijian Zhao, Wei Wang, Falin He, Kun Zhong, Shuai Yuan, Zhiguo Wang

Original Papers, Volume 27, October, Issue 3

KEYWORDS: critical value; quality indicators; extra-analytical phase

https://doi.org/10.11613/BM.2017.030707

Minimum requirements for the estimation of measurement uncertainty: Recommendations of the joint Working group for uncertainty of measurement of the CSMBLM and CCMB

Ivana Ćelap, Ines Vukasović, Gordana Juričić, Ana-Maria Šimundić

Review, Volume 27, October, Issue 3

KEYWORDS: measurement uncertainty; recommendations; harmonization; analytical phase

https://doi.org/10.11613/BM.2017.030502

Pneumatic tube system transport does not alter platelet function in optical and whole blood aggregometry, prothrombin time, activated partial thromboplastin time, platelet count and fibrinogen in patients on anti-platelet drug therapy

Dietmar Enko, Harald Mangge, Andreas Münch, Tobias Niedrist, Elisabeth Mahla, Helfried Metzler, Florian Prüller

Original Papers, Volume 27, February, Issue 1

KEYWORDS: platelets; platelet aggregation; platelet function tests; clinical laboratory services; preanalytical phase

https://doi.org/10.11613/BM.2017.023

Preanalytical investigations of phlebotomy: methodological aspects, pitfalls and recommendations

Cristiano Ialongo, Sergio Bernardini

Review, Volume 27, February, Issue 1

KEYWORDS: phlebotomy; preanalytical phase; statistical data analysis; methods

https://doi.org/10.11613/BM.2017.020

External quality assessment of medical laboratories in Croatia: preliminary evaluation of post-analytical laboratory testing

Jasna Lenicek Krleza, Adrijana Dorotic, Ana Grzunov

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: post-analytical phase; standardization; external quality assessment; questionnaire

https://doi.org/10.11613/BM.2017.018

Preanalytical external quality assessment of the Croatian Society of Medical Biochemistry and Laboratory Medicine and CROQALM: finding undetected weak spots

Nora Nikolac, Jasna Lenicek Krleza, Ana-Maria Simundic

Special Issue: External Quality Assessment in Laboratory Medicine - Original Papers, Volume 27, February, Issue 1

KEYWORDS: preanalytical phase; external quality assessment; laboratory error

https://doi.org/10.11613/BM.2017.017

Timeliness “at a glance”: assessing the turnaround time through the six sigma metrics

Cristiano Ialongo, Sergio Bernardini

Original papers, Volume 26, February, Issue 1

KEYWORDS: turnaround time; statistical data analysis; quality control; healthcare quality indicator; postanalytical phase

https://doi.org/10.11613/BM.2016.010

The knowledge and understanding of preanalytical phase among biomedicine students at the University of Zagreb

Lora Dukic, Anja Jokic, Josipa Kules, Daria Pasalic

Original papers, Volume 26, February, Issue 1

KEYWORDS: survey; education; preanalytical phase

https://doi.org/10.11613/BM.2016.009

Unnecessary repeated total cholesterol tests in biochemistry laboratory

Suleyman Demir, Nergiz Zorbozan, Elif Basak

Original papers, Volume 26, February, Issue 1

KEYWORDS: unnecessary repeated cholesterol test; cholesterol retest interval; reference change value; laboratory costs; preanalytical phase; test requesting

https://doi.org/10.11613/BM.2016.007

Effectiveness of citrate buffer-fluoride mixture in Terumo tubes as an inhibitor of glycolysis

Graziella Bonetti, Mariarosa Carta, Martina Montagnana, Claudia Lo Cascio, Anna Rita Bonfigli, Andrea Mosca, Roberto Testa

Original papers, Volume 26, February, Issue 1

KEYWORDS: glucose; pre-analytical phase; sodium fluoride; citrate acidification; stability

https://doi.org/10.11613/BM.2016.006

Failure to review STAT clinical laboratory requests and its economical impact

Enrique Rodriguez-Borja, Celia Villalba-Martinez, Esther Barba-Serrano, Arturo Carratala-Calvo

Original papers, Volume 26, February, Issue 1

KEYWORDS: quality indicators; health care; extra-analytical phase; total quality management; clinical laboratory information systems

https://doi.org/10.11613/BM.2016.005

The effect of extremely high glucose concentrations on 21 routine chemistry and thyroid Abbott assays: interference study

Serap Çuhadar, Mehmet Köseoğlu, Yasemin Çinpolat, Güler Buğdaycı, Murat Usta, Tuna Semerci

Original papers, Volume 26, February, Issue 1

KEYWORDS: assay interference; glucose interference; preanalytical phase; creatinine; Jaffe kinetic assay; thyroid function tests

https://doi.org/10.11613/BM.2016.004

Abnormal gel flotation caused by contrast media during adrenal vein sampling

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Matteo Gelati, Antonella Bassi, Alberto Contro, Francesca Pizzolo, Gian Cesare Guidi

Case Report, Volume 26, October, Issue 3

KEYWORDS: preanalytical phase; blood specimen collection; contrast media; gels; phlebotomy

https://doi.org/10.11613/BM.2016.047

Indications for laboratory tests in primary care: assessment of the most frequent indications and requests with blank clinical information

Maria Salinas, Maite López-Garrigós, Emilio Flores, Maria Leiva-Salinas, Patricia Esteban, Miguel Ahumada, Carlos Leiva-Salinas

Short communication, Volume 26, October, Issue 3

KEYWORDS: clinical laboratory; pre-analytical phase; primary care; quality indicators; test request

https://doi.org/10.11613/BM.2016.045

The influence of sample freezing at – 80 °C for 2–12 weeks on glycated haemoglobin (HbA) concentration assayed by HPLC method on Bio-Rad D-10 auto analyzer

Katarzyna Bergmann, Grazyna Sypniewska

Original Papers, Volume 26, October, Issue 3

KEYWORDS: glycated haemoglobin; diabetes; sample storage; high performance liquid chromatography; preanalytical phase

https://doi.org/10.11613/BM.2016.038

Continuous quality control of the blood sampling procedure using a structured observation scheme

Tine Lindberg Seemann, Mads Nybo

Original papers, Volume 26, October, Issue 3

KEYWORDS: observation; phlebotomy; preanalytical phase; quality control

https://doi.org/10.11613/BM.2016.037

Phlebotomy, a bridge between laboratory and patient

Cristiano Ialongo, Sergio Bernardini

Review, Volume 26, February, Issue 1

KEYWORDS: phlebotomy; venipuncture; laboratory testing; preanalytical phase; preanalytical variability; patient safety; evidence based medicine

https://doi.org/10.11613/BM.2016.002

Automatic laboratory-based strategy to improve the diagnosis of type 2 diabetes in primary care

Maria Salinas, Maite López-Garrigós, Emilio Flores, Maria Leiva-Salinas, Javier Lugo, Francisco J Pomares, Alberto Asencio, Miguel Ahumada, Carlos Leiva-Salinas

Original papers, Volume 26, February, Issue 1

KEYWORDS: type 2 diabetes; HbA1c; diagnosis; preanalytical phase; test request appropriateness; costs; cost analysis

https://doi.org/10.11613/BM.2016.013

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Giuseppe Lippi, Patrizia Bonelli, Laura Bonfanti, Gianfranco Crevellin

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; hemolysis; blood specimen collection; catheter; emergency department

https://doi.org/10.11613/BM.2015.008

Comparison of blood ethanol stabilities in different storage periods

Fatma Emel Kocak, Ozben Ozden Isiklar, Havva Kocak, Ayfer Meral

Original papers, Volume 25, February, Issue 1

KEYWORDS: preanalytical phase; ethanol; stability; storage temperature

https://doi.org/10.11613/BM.2015.006

Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator

Maria Salinas, Maite López-Garrigós, Emilio Flores, Ana Santo-Quiles, Mercedes Gutierrez, Javier Lugo, Rosa Lillo, Carlos Leiva-Salinas

Original papers, Volume 25, February, Issue 1

KEYWORDS: Preanalytical phase; errors in laboratory medicine; balanced scorecard; patient safety

https://doi.org/10.11613/BM.2015.005

Larger differences in utilization of rarely requested tests in primary care in Spain

Maria Salinas, Maite López-Garrigós, Emilio Flores, Joaquín Uris, Carlos Leiva-Salinas

Original papers, Volume 25, October, Issue 3

KEYWORDS: primary care; laboratory proficiency testing; clinical laboratory services; test requesting; preanalytical phase

https://doi.org/10.11613/BM.2015.041

Confidence level in venipuncture and knowledge on causes of in vitro hemolysis among healthcare professionals

Dragana Milutinović, Ilija Andrijević, Milijana Ličina, Ljiljana Andrijević

Original papers, Volume 25, October, Issue 3

KEYWORDS: hemolysis; patient safety; phlebotomy; medical staff; questionnaire; preanalytical phase

https://doi.org/10.11613/BM.2015.040

Hemolysis from a nurses’ standpoint – survey from four Croatian hospitals

Adrijana Dorotić, Dragana Antončić, Vanja Radišić Biljak, Dara Nedić, Andjelo Beletić

Original papers, Volume 25, October, Issue 3

KEYWORDS: hemolysis; nurses; survey; preanalytical phase

https://doi.org/10.11613/BM.2015.039

Specimen rejection in laboratory medicine: Necessary for patient safety?

Zeliha Gunnur Dikmen, Asli Pinar, Filiz Akbiyik

Original papers, Volume 25, October, Issue 3

KEYWORDS: clinical laboratory services; total quality management; patient safety; preanalytical phase; preanalytical error

https://doi.org/10.11613/BM.2015.037

Capillary blood sampling: national recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine

Jasna Lenicek Krleza, Adrijana Dorotic, Ana Grzunov, Miljenka Maradin

Review Article, Volume 25, October, Issue 3

KEYWORDS: recommendations; capillary blood; blood specimen collection; standardization; preanalytical phase

https://doi.org/10.11613/BM.2015.034

How well are pregnant women in Croatia informed about the oral glucose tolerance test?

Patricija Bankovic Radovanovic, Marija Kocijancic

Research Article, Volume 25, June, Issue 2

KEYWORDS: preanalytical phase; oral glucose tolerance test; survey; patient education; gestational diabetes

https://doi.org/10.11613/BM.2015.023

Plasma centrifugation does not influence thrombin-antithrombin and plasmin-antiplasmin levels but determines platelet microparticles count

Ewa Stępień, Krzysztof Gruszczyński, Przemysław Kapusta, Artur Kowalik, Iwona Wybrańska

Research Article, Volume 25, June, Issue 2

KEYWORDS: cell-derived microparticles; blood coagulation tests; centrifugation; preanalytical phase

https://doi.org/10.11613/BM.2015.022

Croatian survey on critical results reporting

Lara Milevoj Kopcinovic, Jasenka Trifunović, Tihana Pavosevic, Nora Nikolac

Research Article, Volume 25, June, Issue 2

KEYWORDS: critical results; laboratory testing; quality indicators; survey; post-analytical phase

https://doi.org/10.11613/BM.2015.019

Lipemia: causes, interference mechanisms, detection and management

Nora Nikolac

Review, Volume 24, February, Issue 1

KEYWORDS: lipemia interference; laboratory error; preanalytical phase; interference testing; biological variation

https://doi.org/10.11613/BM.2014.008

Evaluation of the BD Vacutainer® RST blood collection tube for routine chemistry analytes:clinical significance of differences and stability study

Marija Kocijancic, Jelena Cargonja, Alma Delic-Knezevic

Original papers, Volume 24, October, Issue 3

KEYWORDS: preanalytical phase; blood specimen collection; serum; test tube; evaluation

https://doi.org/10.11613/BM.2014.039

Contamination of lithium heparin blood by K2-ethylenediaminetetraacetic acid (EDTA): an experimental evaluation

Gabriel Lima-Oliveira, Gian Luca Salvagno, Elisa Danese, Giorgio Brocco, Gian Cesare Guidi, Giuseppe Lippi

Original papers, Volume 24, October, Issue 3

KEYWORDS: contamination; EDTA; patient safety; preanalytical variability; total quality management; preanalytical phase

https://doi.org/10.11613/BM.2014.038

Abnormal gel flotation in a patient with apperant pneumonia diagnosis: a case report

Fethullah Gerin, Dilber Coban Ramazan, Ozgur Baykan, Onder Sirikci, Goncagul Haklar

Case report, Volume 24, February, Issue 1

KEYWORDS: separator gel; preanalytical phase; blood collection tube; floating gel; hyperproteinemia

https://doi.org/10.11613/BM.2014.021

The effect of storage time and freeze-thaw cycles on the stability of serum samples

Serap Cuhadar, Mehmet Koseoglu, Aysenur Atay, Ahmet Dirican

Original papers, Volume 23, February, Issue 1

KEYWORDS: preanalytical phase; serum; stability; storage; temperature

https://doi.org/10.11613/BM.2013.009

Effect of sample type, centrifugation and storage conditions on vitamin D concentration

Ayfer Colak, Burak Toprak, Nese Dogan, Fusun Ustuner

Original papers, Volume 23, October, Issue 3

KEYWORDS: centrifugation; temperature; stability; vitamin D; preanalytical phase

https://doi.org/10.11613/BM.2013.039

The effective reduction of tourniquet application time after minor modification of the CLSI H03-A6 blood collection procedure

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Original papers, Volume 23, October, Issue 3

KEYWORDS: venous stasis; preanalytical phase; tourniquets; phlebotomy; practice guidelines

https://doi.org/10.11613/BM.2013.037

Exhaled breath condensate – from an analytical point of view

Slavica Dodig, Ivana Čepelak

Review, Volume 23, October, Issue 3

KEYWORDS: exhaled breath condensate; analysis; preanalytical phase; respiratory diseases

https://doi.org/10.11613/BM.2013.034

Croatian Society of Medical Biochemistry and Laboratory Medicine: national recommendations for venous blood sampling

Nora Nikolac, Vesna Šupak-Smolčić, Ana-Maria Šimundić, Ivana Ćelap

Review, Volume 23, October, Issue 3

KEYWORDS: phlebotomy; venous blood; recommendations; health planning; laboratory errors; preanalytical phase

https://doi.org/10.11613/BM.2013.031

Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Geraldo Picheth, Gian Cesare Guidi

Case report, Volume 23, June, Issue 2

KEYWORDS: clinical laboratory techniques; preanalytical phase; laboratory variability; blood specimen collection; EDTA contamination carryover

https://doi.org/10.11613/BM.2013.026

Preanalytical phase – a continuous challenge for laboratory professionals

Ana-Maria Simundic, Giuseppe Lippi

Editorial, Volume 22, June, Issue 2

KEYWORDS: preanalytical phase; errors; quality indicators; phlebotomy; blood sampling

https://doi.org/10.11613/BM.2012.017

New ways to deal with known preanalytical issues: use of transilluminator instead of tourniquet for easing vein access and eliminating stasis on clinical biochemistry

Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Cristovão Luis Pitanguiera Manguera, Nairo M. Sumita, Geraldo Picheth, Gian Cesare Guidi, Marileia Scartezini

Original papers, Volume 21, June, Issue 2

KEYWORDS: phlebotomy and blood collection; pre analytical phase; quality management system in clinical laboratory; transillumination; venous stasis.

https://doi.org/10.11613/BM.2011.024

Development of a preanalytical errors recording software

Giuseppe Lippi, Patrizia Bonelli, Rossana Rossi, Mirco Bardi, Rosalia Aloe, Alberta Caleffi, Enrichetta Bonilauri

Original papers, Volume 20, February, Issue 1

KEYWORDS: errors; laboratory testing; computer program; informatics; extra-analytical phase

https://doi.org/10.11613/BM.2010.011

Self reported routines and procedures for the extra-analytical phase of laboratory practice in Croatia - cross-sectional survey study

Lidija Bilić-Zulle, Ana-Maria Simundic, Vesna Šupak Smolčić, Nora Nikolac, Lorena Honović

Original papers, Volume 20, February, Issue 1

KEYWORDS: clinical chemistry tests; extra-analytical phase; quality of health care; questionnaire

https://doi.org/10.11613/BM.2010.008

Total quality in laboratory diagnostics. It's time to think outside the box

Giuseppe Lippi, Ana-Maria Simundic

Editorial, Volume 20, February, Issue 1

KEYWORDS: patient safety; laboratory diagnostics; preanalytical phase; errors; quality

https://doi.org/10.11613/BM.2010.001

Notification of critical values

Mario Plebani, Elisa Piva

Special issue, Volume 20, June, Issue 2

KEYWORDS: critical values; notification of critical values; clinical laboratories; post-analytical phase; errors in laboratory medicine

https://doi.org/10.11613/BM.2010.021

Quality and diagnostic perspectives in laboratory diagnostics

Mathias M. Müller

Special issue, Volume 20, June, Issue 2

KEYWORDS: laboratory medicine; diagnostic process; pre-analytical phase; post-analytical phase

https://doi.org/10.11613/BM.2010.016

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